Can a person with A+ blood type donate a kidney to a person with O type blood?

Generally, someone with blood type A+ cannot donate to a person with blood type O, because blood type O patients will have preformed antibodies to the “A” antigen. This will result in a hyperacute rejection. In a very few centers, there are experimental protocols to do this type of transplant using experimental treatments, but it is risky and risks causing acute rejection episodes.
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