Patients with chronic kidney disease (CKD) have a markedly increased risk of kidney failure when given dye for a heart angiogram. The worse the CKD, the more likely that this will occur. Your friend should follow the advice of the nephrologist who saw him at the hospital. It is important to have a specific diagnosis as to the cause of the kidney disease. If the cause is acute kidney injury, then kidney function may improve and the angiogram may be possible. If this is CKD, then the angiogram could cause your friend to require dialysis treatments. If this is CKD, there are no treatments other than dialysis that will lower the serum creatinine.