I would not double up on medications, but this is a concern. Missed doses can result in rejection and loss of the kidney. I suggest that you contact your transplant center when you miss a dose. This will let them know that they may need to adjust the interpretation of your transplant drug levels, especially for tacrolimus. In addition, tacrolimus now comes as a single, once daily dosing form and this could be a consideration for you. Mycophenolate comes only in twice daily dosing, so you would still have to take some drugs twice daily.
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