Does a high uric acid level cause an increase in a creatinine level?

This is a problem of the chicken or the egg.  An elevated blood uric acid level can be associated with acute and chronic gouty arthritis.  An elevated blood uric acid level over many years can also be associated with kidney damage and cause “gouty nephropathy” which is a chronic kidney disease (CKD).  It is also true that CKD by itself can cause an elevated blood uric acid level which can lead to gout.  So, while there is no evidence that an elevated blood uric acid level directly increases the serum creatinine, it is true that gout can be a result of CKD and CKD can also cause gout.

 

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