Calciphylaxis of the skin is a relatively rare, very painful and serious complication of kidney failure and dialysis patients. There are no standardized treatments that are universally recommended for this disease as it is so uncommon. Surgical removal of the calcified plaques is not recommended and if done, usually results in worsening of the disease and more extension of the ulceration. Many treatments have been tried including hyperbaric oxygen, sodium thiosulfate, and daily dialysis. In patients with hyperparathyroidism, removal of the parathyroid glands (total parathyroidectomy) is commonly recommended. If coumadin (warfarin) is being administered, this medication should be stopped. Many of these patients must be treated in a specialized burn unit for specialized wound and skin care.
I recommend consultation with your mother’s nephrologist to explore options that might be available for her treatment.