Since eGFR appears to indicate a bodies ability to “filter” out harmful elements in blood – what are the best ways to “clean” the filter just like I would with my HVAC air conditioner filter or vacuum filter or my car’s air & oil filters, et al? In particular, does drinking a lot of water (or other liquid or process you might suggest) have the ability to improve or refresh the kidneys “filtering ” function?

The filters (glomeruli) do not require cleaning.  The body is very adept at maintaining the integrity of the glomeruli as long as other disease (hypertension, diabetes, atherosclerosis, and glomerulonephritis) does not cause damage.

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