My wife is testing for pituitary issues, and had a 2.3 g/24hr reading on her creatinine. The lab showed this was high, but somewhat still within the range. At the age of 40, and a caucasian, is this a reading that we need to be concerned about?

The result you provide suggests that this is a result from a 24 hour urine collection and represents the total amount of creatinine excreted into the 24 hour collection at 2300 milligrams or 2.3 grams.  This would be somewhat high for a female but could be the case if your wife is relatively muscular.  As long as her blood creatinine is normal and her estimated glomerular filtration rate (eGFR) is normal, a high urinary excretion of creatinine does not usually represent any disease.


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