How high can creatinine rise until gfr and egfr drops to 15% – 10%? Meaning, how high a creatinine number can the kidneys handle before it makes gfr and egfr really drop?

There is a direct relationship between the serum creatinine and the estimated glomerular filtration rate (eGFR).  The higher the serum creatinine goes, the eGFR falls accordingly.  You can explore this relationship with the equation on our web site.  You can enter various numbers into the equation and learn the relationship for yourself. The equation can be accessed at:


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