The decision to accept someone as a kidney donor is dependent on the judgement and protocols established by the individual transplant centers. There are no nationwide guidelines for accepting a kidney donor. Hence, the decision to reject you as a kidney donor is unique to the transplant center that you applied to. If you wish, you and your wife can apply to another transplant center for a second opinion. Your wife must first be accepted as a participant on their list and then you can be evaluated as a donor for a second opinion.