My sister creatinine level is 5.4. We are under medication but still increasing day by day. Doc suggest for transplant. Is that only way? Is there any other medicine to cure? I don’t want dialysis nor transplant. What to do? Her age is 48 yrs.

I am unable to make a specific diagnosis based on the information that you present.  There are many causes of acute and chronic kidney disease (CKD).  You need to consult with a nephrologist for a specific diagnosis and this will lead to specific treatment of your CKD.

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