Hello, I am 63 years old and have stage 3A CKD where my creatinine fluctuates between 1.4 – 1.6. I have high uric acid (8.6) and every now and then I get some pretty horrific gout attacks. Are any of the medications to lower uric acid safe to take? I currently take 80mg Telmisartan. I understand that Losartan can lower uric acid levels. Does it make sense to switch to Losartan? Thanks.

You are correct that Losartan does have some uric acid lowering properties and may be used in patients with gout and elevated serum uric acid. I suggest that you review this information with your physician and see if Losartan would be an appropriate substitute for Temisartan in your situation. Other drugs that lower the serum uric acid levels include Allopurinol and Uloric (febuxostat). The dose of Allopurinol may occasionally have to be modified in patients with chronic kidney disease (CKD). The blood uric acid level should be targeted to less than 6.0 milligrams per deciliter (mg/dl) in order to prevent attacks of gout.

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