Category Archives: Acute Kidney Injury

My father is a CKD patient; CKD stage 4, eGFR 23ml/min. Now he has been suffering from Shingles (Herpes zoster) since last five days. Can he take acyclovir (Acivir 400 DT)? The prescribed dose is Acivir 400 DT 4 times a day.

I cannot recommend doses of acyclovir without performing a complete history and physical examination. The typical dose of acyclovir recommended for treating shingles (herpes zoster) is Acyclovir 800 milligrams five times daily for seven days. The dose of acyclovir must … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, GFR, Kidney Stones, Kidney-Related Health Questions

Hi, I have a relative who is a known case of heart failure for years on regular treatment and follow up. Two weeks ago, added Atorvastatin 10 mg and Candesartan 4 mg to his treatment regimen. Few days later he had a renal function test that showed an increase in Urea and Creatinine, upon which his doctor stopped the Candesartan, and when the test was repeated 24 hours later, the Urea and Creatinine levels have already started to decrease. After two days, he was given oral Amoxicillin 1.5 gm per day because of his chest infection and he finished his 7 day course of antibiotics, but on the last day of the course he deteriorated, became confused and his edema was worse than ever. Furthermore, he didn’t pass any urine for over a day. He was taken to the emergency, admitted and started on renal replacement therapy. My question is, could the amoxicillin have caused this deterioration? His renal function results have always been normal, his kidneys healthy, and the deterioration only started with the Candesartan. However, the kidney function started to improve upon cessation of this medication. We are confused at what triggered this tragedy and wondering for how long should the replacement therapy continue, and whether anything else can be done. Thank you for your time.

I am unable to make a specific diagnosis based on the information that you present. There are many possibilities. It is very common for Candesartan and other ARB agents to produce an increase in the serum creatinine and Blood Urea … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Serum Creatinine

My wife has Stage 3 CKD & is in the hospital battling colitis & they are giving her antibiotics. They told me today that her kidneys are getting worse. Is there anything that can slow the damage down or is possible to heal some of the damage after she heals from the colitis? Thank You.

The kidneys are likely suffering from acute kidney injury (AKI) as a result of the infection. In patients with pre-existing chronic kidney disease (CKD) this AKI can sometimes be reversed but this is not always predictable because of the different … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Nephrologist

Hi doctor. My father is age 52 and he is suffering from urine infection and his creatinine count is now 6. He has a back pain since 10 years and due to that he consumed pain killers as well. So now he is going through dialysis for the first time today. What will be the best treatments to reduce the creatinine count?

I am unable to tell if your father’s kidney disease is acute kidney injury or chronic kidney disease (CKD). The first thing to do is to determine if the kidney disease is reversible. This will require further testing. If the … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Dialysis, Kidney-Related Health Questions, Transplantation

My father has creatinine level 4.67. How much chance of a recovery and what is the exact way to live long without dialysis?

I am unable to determine if your father has acute or chronic kidney disease. It is first necessary to determine if your father has acute or chronic kidney disease. Once this is known, then a specific diagnosis can often be … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Dialysis, Kidney-Related Health Questions, Nephrologist, Transplantation

My Aunt, 53 year old, has got chronic kidney disease. Her kidneys got shrinked and her kidney size (right) 7.2X2.5 cm & (left) 8.4X3.3 cm. Creatinine serum level is 9.86 mg/dL. Please suggest urgent.

The information that you present suggests very advanced kidney disease but I cannot tell if this is acute or chronic kidney disease. I suggest that your aunt consult with a nephrologist for diagnosis and appropriate treatment.

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Nephrologist

Thank you for your insight: I have chronic progressive multiple sclerosis causing a neurogenic bladder. Use of an indwelling cath resulted in a in-hospital treatment and UTI’s. Currently, my regime is self cath 3X/day and that still doesn’t seem good enough to avoid UTIs. As I read more, it appears chronic MS can cause chronic elevated blood pressure as well; causing damage to the kidneys which further complicates the BP issue. My Urologist seems clueless in understanding this. AM I WRONG? Would you PLEASE suggest reading material/advice on aggressively fighting this problem that I would enable better discussion of this issue with my doc. A most sincere thank you!

The problem that you describe is a urological problem. I am a nephrologist. The problem relates to recurring blockage and infection in the kidney that results in recurring episodes of acute kidney injury. You may need to also consult with … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Kidney-Related Health Questions, Nephrologist

My GFR has dropped from 94 to 33 in 2 years. I’m going to a specialist. I’m really scared. How can a seemingly healthy male, 59, go down this far so quickly?

I am unable to provide a specific diagnosis based on the information that you present. There are many types of acute kidney injury and glomerulonephritis that could be considered. Your consultation with a nephrologist is appropriate. Further testing will be … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Glomerulonephritis, Kidney-Related Health Questions, Nephrologist

My sister is having chronic kidney disease and her age is 27. Creatinine is 5.3, eGFR is 10ml, urea is 88. She has an issue in her heart vein as well. Is kidney transplantation a must? Is there any way to cure? If at all kidney transplantation is required, which surgery should take place first. Kidney or Heart?

I am unable to provide medical advice without performing a complete history and physical examination. Your sister appears to have advanced kidney disease, but I cannot tell if this is acute kidney injury or chronic kidney disease (CKD). Your sister … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Transplantation

One of my family members did their regular test and we found that his CREATININE SERUM is 4.68 mg/dL. I want to know the following: 1) How much we should worry about? 2) What should we be doing now to control it? As weight seems to be going down very fast. Any help would be very helpful.

The serum creatinine that you quote is very abnormal and should be investigated further by your family member’s physician. I am unable to make any specific diagnosis based on the information that you present. I suggest further testing to see … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Serum Creatinine