Category Archives: Blood/Urine Testing For Kidney Disease

My brother is awaiting a second kidney transplant. His first transplant was 7 years back. Dr’s are saying his PRA levels are very high. He has HLA Class I PRA -7% and HLA Class II PRA -91% (tests done in Feb 2017) What are options to reduce PRA and can continuous dialysis for some more time reduce PRA? He started dialysis again in Feb this year and he had few blood transfusions in Jan & feb this year.

Panel reactive antibodies (PRA’s) are immune proteins in the blood that are non-specifically directed against potential kidney donors.  In some cases, the exact Human Lymphocyte Antigen (HLA) type can be detected, but in some cases, we do not know the … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Living Donation, Symptoms and Side Effects, Treatments

My wife is 51 years old. Her creatinine level was always below 0.97. On 18 April, her creatinine level rose at 1.41 and gfr was at 51. On 25 May her creatinine level was 137.6 umol/L and gfr went down to 37. In the 1st investigation period she was having fever and in the 2nd investigation period she had coughing. Now her creatinine level is 1.55 even though she is on 30gm protein level diet plan. What is the cause of quick drop of her gfr?

I am unable to make a specific diagnosis based on the information that you present.  This appears to be something that is causing acute kidney injury.  I recommend consultation with your physician and further testing as to why she is … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diet/Nutrition, GFR, Kidney Failure, Kidney-Related Health Questions, Symptoms and Side Effects

I have a family history of CAD, hypertension and kidney failure. I am 40 year old, normal weight, non-hypertensive, non-smoking, non-drinking female taking only levothyroxine for my thyroid. All of my labwork is within normal range except my GFR, which is 59. What does this mean for my kidneys?

Normal kidney function is to have an estimated glomerular filtration rate (eGFR) greater than 60 milliliters per minute per 1.73 meters squared. I am unable to make a specific diagnosis based on the information that you present.  This may be … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Symptoms and Side Effects

I am male 82 years old. I tested today for 2.0 creatinine. I have been taking for a long period of time 3mg a day of Ativan and 400 mg of Ibuprofen. Could these medicines affect the creatinine level and if so would it raise them that much? About a year ago, it was less than 1.3 and I have only tested again this year to find the high increase.

Ibuprofen can reduce kidney function and should not be taken long term.  I suspect that the abnormalities in your kidney function may be related to the ibuprofen.  I suggest that you stop this medication and then see your primary care … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Symptoms and Side Effects, Treatments

Below are the results of my latest blood work. This was reordered because my potassium on earlier bloodwork was 5.9. Based on below would you suspect some sort of kidney problem and should I consult with a specialist? Order Date: 06/06/2017 Collection Date: 06/12/2017 09:53:00 Received: 06/12/2017 16:40:03 Report: 06/12/2017 16:23:00 BASIC METABOLIC PANEL NAME VALUE REFERENCE RANGE LAB F GLUCOSE 104 H 65-99 (mg/dL) MI – Fasting reference interval – For someone without known diabetes, a glucose value – between 100 and 125 mg/dL is consistent with – prediabetes and should be confirmed with a – follow-up test. F UREA NITROGEN (BUN) 25 7-25 (mg/dL) MI F CREATININE 0.91 0.50-1.05 (mg/dL) MI – For patients >49 years of age, the reference limit – for Creatinine is approximately 13% higher for people – identified as African-American.

I do not identify any kidney disease based on the information that you present.  In some cases, laboratory errors may occur. I suggest that you have urine testing for blood, protein and infection as well as the blood testing.  I … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing

After a kidney stone removal operation, can the scar be a vertical line – running from the lower rib cage to the navel (belly button)? Can you please provide me with photo’s of – or refer me to where I can download photo’s of the scar(s) a patient could have after such a procedure ? Thank you very much for your time.

I am a nephrologist and not a surgeon.  A urologist performs kidney surgery and I have no expertise in surgery and do not know where different incisions may be made for different surgeries.  I suggest that you ask your urologist … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Urological Issues

I am a healthy 24 year old white male taking 1 gram of Valtrex/day for the last 18 months. I have no symptoms but on a routine blood test my kidney functions were Cr of 1.87, BUN of 27, BUN/Cr ratio of 14 and a eGFR of 49. Urinalysis shows no protein. I discontinued Valtrex 5 days ago and will have a second blood test plus a 24 hr urine collection. My question is: is increasing intake of fluids and possibly consuming cherry juice as it’s done for gout help my kidneys recover from crystal deposition? I have no medical problems, my BP is 110/70.

The testing that you describe, if it remains abnormal for more than 3 months, does suggest that you have chronic kidney disease (CKD).  I am unable to make a specific diagnosis based on the information that you present.  If you … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Laboratory Testing, Symptoms and Side Effects, Treatments

I underwent a nephrectomy on April 3 whereby my left kidney and large tumor was removed. I have had a number of blood tests since then and have noticed that my BUN and creatinine are not within normal ranges BUN (35) creatinine (1.70) and my egfr is currently (June 13,) at 40. Should I be concerned at this point? I assume that without one kidney it would be low.

After undergoing removal of a kidney, your kidney function tests will be abnormal and the estimated glomerular filtration rate (eGFR) will be low.  After removal of one kidney, I would expect the eGFR to be in the range of 50 … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrectomy / One kidney, Symptoms and Side Effects, Treatments

Hi Dr. Spry — 39/yo amateur bodybuilder here. I learned a couple years ago that I have kidney dysplasia, one side completely polycystic kidney and the other mildly hypertrophied. I am used to my creatinine running high (over 1.3) and GFR just shy of 60. However some recent labs have disturbed me! Serum Creatinine 2.0 — note that I weigh ~100kg/225lbs largely muscle, this has crept up over time correlated with my weight gain (1.3, 1.5, 1.7, 1.8…) 24 hr urine contained 2.3g protein! — note that I didn’t know not to train, and trained legs (intensely) the day of sample collection eGFR 35-40 — could this be related to creatinine? BUN 44 — Note that I have been on very high protein diet, upwards of 4g/kg (400-450g total) I have been on Losartan for hypertension for about a year and a half. My BP is usually well controlled. Due to some other chronic illness (HIV, well controlled CD4 healthy normal range) I track my lab values in a spreadsheet. I can see a correlation between my weight/muscle gains from 200-220lbs and the increased serum creatinine and reduced eGFR. When I learned that I had the kidney dysplasia I had a proper radioactive measurement, and all I have in my notes is that GFR was fine and healthy for one kidney. Questions: 1. Is it possible/believable that this is all caused by my atypical muscle mass and intense training? (High creatinine, thus low GFR, exercise induced proteinuria) 2. With the kidney dysplasia, do I technically have CKD with basically 50% of a normal person’s kidney function? I am freaked out thinking that I’ve suddenly in the last 9-12 months had some sudden kidney injury!

By definition, you have chronic kidney disease (CKD) because the dysplastic polycystic kidney has been present for at least three months.  Hence, you do have reduced kidney function.  The body building that you are doing will increase the serum creatinine … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects, Treatments

My labs came back showing creatinine 0.8, no protein in my urine yet it showed my egfr as 73. I am a 54 Caucasian female and was wondering why my GFR shows 84 when I use an online gfr calculator. Why does my labs (blood work) show it much lower?

The online calculator calculates the estimated glomerular filtration rate (eGFR) in units that include your body size and is adjusted to a body surface area (BSA) of 1.73 meters squared.  The number can be changed by either including your body … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing