Category Archives: Clinical Trials/Studies

I read about the University of California’s “Kidney project” recently. It appears that the human trials are expected to start in 2017. What are your views on the project and its potential? Are there any other break through research initiatives on the CKD currently on including using stem cells that may potentially be a game changer.

Research into kidney disease and treatment of kidney disease has many fronts and all seem to hold some promise.  The research must be done in order to determine if they are safe and effective treatments.  The most important feature is … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Clinical Trials/Studies, Kidney-Related Health Questions

I have participated in medical research unrelated to kidneys for many years. In the last few years, this has involved functional PET scans. I am now 84 and based on GFR I have been placed in CKD. Is there any research or medical opinions about ability of radioactive tracers damaging the kidneys?

I am unaware of any information about the use of radioactive tracers and radioactivity causing chronic kidney disease (CKD).  I know of no literature on the subject.

Posted in Ask the Doctor, Chronic Kidney Disease, Clinical Trials/Studies, Kidney-Related Health Questions

Are their any studies where acupuncture is used to help slow kidney disease and control blood pressure?

I am not aware of any scientific studies that have examined the use of acupuncture in the treatment of kidney disease or high blood pressure.  However, there may have been case studies conducted that I am not familiar with.

Posted in Ask the Doctor, Chronic Kidney Disease, Clinical Trials/Studies, Kidney-Related Health Questions, Treatments

What is the status of iRAD &/or similar implantable artificial kidney solutions? Best that I can find is clinical trials are set to start in 2017.

I will assume that you are talking about the Renal Tubule Assist Device being studied by Dr. David Humes.  As of the last publication that I am aware of, the device has only been used in animals and limited studies … Continue reading

Posted in Ask the Doctor, Clinical Trials/Studies

I have been on peritoneal dialysis for four years. I am just 76. I had nephritis due to scarlet fever as a child. Throughout my life I was very fit and active. I worked until I was 69. When I started on dialysis I had a GFR of 6-7. It is still the same. Most of my blood results are within the normal range. I play golf and do a lot of walking.Seeing as I still have some kidney function could I benefit from stem cell therapy?

Stem cell therapy has not be shown to have any effect on kidney disease or kidney function in controlled trials.  There are currently no stem cell treatments that are current recognized by the Food and Drug Administration (FDA) for treatment of any … Continue reading

Posted in Ask the Doctor, Clinical Trials/Studies, Kidney Failure, Kidney-Related Health Questions

My son is 17; he was diagnosed with FSGS secondary. He has a twin brother. Is stem cell transplant from twin a good treatment and where is this done if so?

Stem cell transplantation is not a recognized treatment for focal segmental glomerulosclerosis (FSGS).  I am not aware of any trials to study this treatment.

Posted in Ask the Doctor, Chronic Kidney Disease, Clinical Trials/Studies, FSGS

I have only 1 kidney as the other was removed around 30 years ago having been malformed probably from birth. I drink a lot of water and drink a glass of cranberry juice daily and have had no problems. Now, I have been asked to participate in a national women’s study to determine whether taking cocoa extract supplements or multivitamins reduces the risk of heart disease, stoke, and cancer. MY question – would taking a cocoa extract have a negative effect on my single kidney ? Thanks, white female, age 77.

I am not aware of any problems associated with cocoa and a single kidney.  Likely the reason for the study is to determine if there are any problems with the medication.  I do not think this particular question has ever … Continue reading

Posted in Clinical Trials/Studies, Kidney-Related Health Questions

Do you know of any research being done to see if any form of oxygen therapy would be safe and effective to reinvigorate kidney cells and function? If I search Newsmax.com for oxygen therapy, it appears there are different forms of the therapy and that it can be used for chronic conditions. Maybe research could be done (without putting lethal pressure on the kidneys) to improve kidney health?

I am unaware of any studies that show a benefit to oxygen in any kidney disease.  In fact, an area of recent research has centered on the deprivation of oxygen to the kidney transiently, in order to protect the kidney … Continue reading

Posted in Ask the Doctor, Clinical Trials/Studies

I was recently [two weeks ago] diagnosed with collagenofibrotic glomerulopathy. Primary finding by Keck USC, then confirmed by Cedars-Sinai Hospital. I understand it is fairly rare condition, but are there any treatments or clinical studies being undertaken for it?

Collagenofibrotic glomerulopathy is a kidney disease grouped among diseases known as “non-amyloid infiltrative diseases of the kidney”.  It is diagnosed by kidney biopsy.  It is very rare.  I have never seen a case in 35 years of experience.  Type III … Continue reading

Posted in Chronic Kidney Disease, Clinical Trials/Studies, Kidney-Related Health Questions

I am about to have a kidney transplant in early March. After my due diligence, I am concerned about the prolonged side effects of the anti rejection medications over the hopeful “long run”. I have read several studies about clinical trials being done at Northwestern, University of Louisville, University of Minnesota and overseas on stem cell/bone marrow transplants that enable you to not have to take anti rejection drugs. Is this something I should consider? I do not want to be debilitated on the other side after surgery with terrible side effects from prolonged dosages of these medications.

These programs are experimental.  You would have to volunteer for research.  At this point, bone marrow transplants are not commonly done to permit routine kidney transplantation and have significant mortality and morbidity associated with this technique including graft versus host … Continue reading

Posted in Clinical Trials/Studies, Kidney-Related Health Questions, Transplantation