Category Archives: GFR

My eGFR has always been between 51 and 53. This month test results shows eGFR of 45. Serum creatinine has always been around 135, this months results are showing 155. Please can you let me know if I need to be worried or if this is an known level of variation. I am already following a healthy diet. Any other suggestions that you can provide to improve my health?

The estimated glomerular filtration rate (eGFR) between 45 and 60 milliliters per minute per 1.73 meters squared is Stage 3a chronic kidney disease (CKD).  These numbers are potentially normal variation and the only way to tell may be to wait … Continue reading

Posted in Ask the Doctor, GFR, Kidney-Related Health Questions, Laboratory Testing

My father age is 67 years, wt is 49 kg . Now creatinine level fluctuates between 2 to 3.9 mg and GFR is 22.7 ml/min. I want to know that how increase in GFR. What is stage of CKD & treatment?

There are no treatments to increase the glomerular filtration rate (GFR).  Decreasing GFR is the result of chronic kidney disease (CKD) that destroys the small filters of the kidney known as glomeruli.  Once those small filter are destroyed, they cannot … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions

Canadian health care guidelines allows a CKD patient not to have dialysis even if the eGFR is 6. They say CKD patients can live a normal life even at that low number without dialysis or kidney transplant. Does America health care go by this guideline?

I begin dialysis when I think that dialysis will benefit my patient.  This is not based on any number, but rather , will dialysis improve the symptoms of my patient to the point that the patient is willing to undergo … Continue reading

Posted in Ask the Doctor, Dialysis, GFR, Kidney Failure, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects, Treatments

Dr Spry, are there different ways of measuring egfr? Following the national foundation’s link my son’s egfr is 46 (with wt and height and 41 without wt and height). But according to his doctor it is 37. His creatinine is 2.1, age 30 and height 70 inches and wt 165.

The estimated glomerular filtration rate (eGFR) can be calculated in at least four different ways in adults and three different ways in children.  This does not include the calculation of the estimated creatinine clearance with a Cockcroft Gault equation.  I … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing

I have stage 4 CKD and I now need a drug that’s safe to take for controlling my heart beat. The Duke hospital put me on Amiodarone HEL, 200 mg. Just a week I started a red rash on my body and legs so I will have to stop the drug. What other drug is safe to use? Thank you for you time and attendance to this request.

I am not a cardiologist and cannot recommend drug treatment without performing a complete history and physical examination.  There are other drugs that can be used, but this would depend on why Amiodarone was used and the heart disease they … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Treatments

Good day. I live in West Africa and I suspect I might have kidney issues. I am sorry for writing, I know your organization operates in your country alone, but I am compelled to write, as we do not have such organizations over here. I have had series of tests conducted with fluctuating results, this coupled with strange symptoms have me very worried to the point of sickness. I lost my brother to ESRD in April last year, which was mostly due to scarring in his kidneys from unknown sources, as we have no family history of the disease. When my brother had a heart attack that led to his death, I attempted CPR, which was unsuccessful. A weeks days later I noticed I had become unwell and was prescribed ciprofloxacin by my doctor. Over time I noticed I urinated more often, never used to initially, but started waking once at night to urinate, had whitish sediments in my urine and felt a weird flowing sensation in my hands and legs, with Numbness/Pins and Needles also being experienced. Later I started having foamy urine which will go away on its own after some days. . . Has just started occurring again. Urinalysis always says no protein, blood or leukocytes. I am not diabetic or hypertensive either. I talked to my GP about it and he said nothing was wrong. But based on gut feelings I decided to go ahead and see a nephrologist who asked me to get a renal function test done. Since then I have had four Renal function tests + urinalysis done and one liver function test, a CT-scan and I am still confused about what is going on. Despite my urinalysis stating no protein repeatedly. Overtime, I have found that on ingesting any form of protein ( Egg whites,165 of milk, etc), my urine becomes very frothy for a day and its been giving me a lot of worries, my urine dipstick home test kit shows normal values, yet I am in doubt of its accuracy. Below is a list of my tests and results arraigned in chronological order. 21/07/2016 Sodium 140mmol/L Potassium 3.9mmol/L Bicarbonate: 27mmol/l Chloride: 101mmol/l Urea: 2.3mmol/L Creatinine 78umol/L Urinalysis: Perfect order No STI’s 02/09/2016 Sodium 138mmol/L Potassium 4.0mmol/L Bicarbonate: 30mmol/l Chloride: 102mmol/l Urea: 3.2mmol/L Creatinine 101umol/L Urinalysis: Perfect order No STI’s 15/11/2016 Sodium 137mmol/L Potassium 3.7mmol/L Bicarbonate: 28mmol/l Chloride: 98mmol/l Urea: 2.4mmol/L Creatinine 110umol/L Urinalysis: Perfect order No STI’s 26/01/2017 Sodium 137.2 mmol/L Potassium 3.2 mmol/L Bicarbonate: 20.6 mmol/l Chloride: 92.2 mmol/l Urea: 3.7 mmol/L Creatinine 168 umol/L Urinalysis: Perfect order No STI’s Doctor requested a re-run a week later 02/02/2017 Sodium 144 mmol/L Potassium 4.1 mmol/L Bicarbonate: 18 mmol/l Chloride: 109 mmol/l Urea: 1.66 mmol/L Creatinine 115 umol/L Urinalysis: Perfect order No STI’s Liver Function Tests Bilirubin(Total) 0.83mg/dl Bilirubin(Direct) 0.11 mg/dl Bilirubin(Indirect) 0.72 mg/dl SGOT(AST) 27.38 U/L SGPT(ALT) 21.79 U/L Alkaline Phosphatase 46.99 U/L GGT 30.78 U/l Total Proteins 7.6 g/dl Albumin 4.5 g/dl Globulin 3.10 g/dl A/G Ratio 1.45 g/dL I have attached a copy of the CT scan report for your perusal. Note, I am 6ft tall and weigh 72kg Thanks and have a great day Regards.

I am not able to make a diagnosis of chronic kidney disease based on the information that you present.  Your symptoms are not typical of kidney disease.  Because you have a family history of kidney disease, I suggest that you … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects, Treatments, Urinary Tract Infection/Pyelonephritis

I had blood tests at the end of May 2016 which indicated I had diabetes but GFR, BUN, Creatinine were all within normal. I had followup blood work January 2017 which showed my diabetes numbers went down to normal range, however GFR, BUN Creatinine all were drastically down (GFR from 78 to 4) and others up. I am frightened and do not know what my next step should be. I am very limited financially.

I suggest that you discuss your concerns with your primary care physician (PCP) and see if referral may be needed.

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing

I was diagnosed last year with stage 3 kidney disease due to overuse of nasties. This diagnosis came after I tried for five years and four doctors to look carefully at my blood work which all but the last one said were fine even though my GFR was as low as 35 one time. I am overweight but since my diagnosis have lost 46 lbs, cut out all sodas, most cookies two a week, all chips, all salt, all cakes and most of the fatty food I ate. My GFR was 52 in April, 45 in August and last week was 42. I was hoping it would level out and my cholesterol went from 151 to 182. My doctors don’t seem concerned but I am worried because I really thought they would level out and stay even I also don’t use any nasties at all any more. Do you have any ideas?

I am unable to provide a specific diagnosis based on the information that you present.  I applaud you for your weight loss and your improved diet.  You appear to have Stage 3 chronic kidney disease (CKD) but I cannot tell … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diet/Nutrition, GFR, Kidney-Related Health Questions, Laboratory Testing, Symptoms and Side Effects

My husband has stage 4 kidney disease. He has been having a great deal of trouble walking. He has fallen many times. At stage 4 could these falls be connected to his kidney disease? He normally can’t walk more than 15 minutes before his legs get wobbly and he looks like they are about to give way. No one has been able to tell us why he has so much trouble. He has been told by neurologists that it is not a neurological problem. His nephrologist says it couldn’t occur to the extent he has it. He doesn’t get much exercise and is getting even less as his legs deteriorate. I don’t know what to do next?

Chronic kidney disease (CKD) should not be a cause of leg weakness.  Stage 4 CKD is commonly associated with weight loss and loss of appetite which can lead to muscle wasting.  However, inactivity alone can also do this.  The longer … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects

Dr Spry; My new Doctor ran a complete panel of blood work and my GFR came back at 52 on 1/3/17, (after two days of symptoms of diarrhea and taking 4 tablets of Imodium to stop it.) She listed in my file stage III CKD. I was unaware I was ever even a stage II! I called her about it and reminded her I had been sick the day before the test and I was fasting. I had submitted a non-fasting blood test before our call and during the call she gave me the results of that test, but had not re-tested for the GFR. When I asked why not she said “If I can catch the blood at the lab, do you want me to run it again?” I said absolutely, I think we need to. Well now she says it came back at 61 and in her words ” I am now normal and has changed my diagnosis in my record as stage II. I don’t know what to think or what to do now. Suggestions?

Chronic kidney disease (CKD) is diagnosed when there has been an abnormal test for at least three months.  If these tests were done days apart, then CKD cannot be diagnosed.  This may have been an episode of acute kidney injury … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Symptoms and Side Effects