Category Archives: GFR

I have been taking Lisinopril 10 12.5 for past 25 yrs. Stage 4 failure and was taken off and creatinine went from 7.5 down to 6.2. Should I continue or find another med for hbp control?

The elevation of the serum creatinine is a normal response for use of ACE-inhibitors such as Lisinopril. By lowering the pressure inside the filters (glomeruli) of the kidney, this causes some decrease in the estimated glomerular filtration rate (eGFR) and … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Serum Creatinine

If a person was born with only one kidney, and is a diabetic, with the kidney only functioning at 28%, where would that place them at risk factor? Would this be at severe or would it be less?

An estimated glomerular filtration rate (eGFR) of 28 milliliters per minute per 1.73 meters squared would suggest Stage 4 chronic kidney disease (CKD). Patients with a single kidney may experience more rapid loss of kidney function over time. I suggest … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Nephrectomy / One kidney

Dear Doctor, I lost my father, 73 years of age, 4 months ago. He was diagnosed with CKD about 11 years ago and his creatinine level was between 2 to 3.5 for most of this item and increased to 4.5 in December 2017. He started dialysis in May 2018 and passed away in Dec 2018 due to upper GI bleed. I have been wondering why he was not recommended for preemptive kidney transplant. He did not suffer from any other co-morbidity. After entering into stage 5, he had a bout of pneumonia and COPD and was suspected of having TB later on. I feel he would have been qualified for transplant before entering into Stage 5 of CKD. Please throw some light on the subject.

Preemptive kidney transplantation is an option for patients who have progressive kidney disease and who have potential living donors. Tuberculosis (TB) and lung disease can be contraindications to transplantation, if these are active. Getting a cadaver donor can be a … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Living Donation, Transplantation

High elevated creatinine levels accompanied by normal 24 hour creatinine clearance, scans and BUN. No protein in urine. Should there be concern? Curious because serum creatinine is said to have many influences and muscle mass is one. But there are also massive 6’2″ 300 pound steroid using men’s lab results that come back normal. Big muscle mass like that with a normal creatinine cause concern to me when looking at a 5’8″ person with higher than normal creatinine and no steroid use. When you are much smaller should that cause someone to be concerned as well? Or is everyone different and you need to look at a person as a whole. Considering both the top tests are co-existing normal or if the tests were not yet taken.

A normal 24 hour urine collection for creatinine clearance is a strong indicator that kidney function is likely normal. As you mention, the serum creatinine tends to go up with increased muscle mass and this can be confusing for estimating … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions, Serum Creatinine

I am Stage 4, creatinine 1.9, GFR 26. For about 6 months, I noticed that my urine turns a milky white, very light brownish color when it sits for extended period of time in commode. Could this have something to do with phosphorus, phosphates, or crystals? If so, please explain which and what causes it. Thank you.

I am unable to determine what could be causing the changes that you describe. The precipitation of crystals and other solutes in the urine on standing has more to do with changes in the acidity of the urine (high or … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions

How do I lower creatinine with diet? And he has protein 65mg. His weight is 174 pound. Please let me know. And can he have kidney transplant now at this point, at stage four? I really appreciate it for the help. Thank you.

I do not know of any dietary adjustment that will improve kidney function and lower the serum creatinine. The goal of treatment of chronic kidney disease (CKD) is to try and preserve remaining kidney function. It is generally not possible … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Nephrologist, Serum Creatinine, Transplantation

My father is a CKD patient; CKD stage 4, eGFR 23ml/min. Now he has been suffering from Shingles (Herpes zoster) since last five days. Can he take acyclovir (Acivir 400 DT)? The prescribed dose is Acivir 400 DT 4 times a day.

I cannot recommend doses of acyclovir without performing a complete history and physical examination. The typical dose of acyclovir recommended for treating shingles (herpes zoster) is Acyclovir 800 milligrams five times daily for seven days. The dose of acyclovir must … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, GFR, Kidney Stones, Kidney-Related Health Questions

I am 60 yrs old. I take medications for blood pressure and cholesterol and both are excellent for the first time in a couple years. I have no diabetes issues. My mother died of stage 4 renal failure. She received dialysis 3 times per week for 5 years before her body gave up. As far as I know, no one else in my family had kidney disease. My BUN runs 15-16. My creatinine runs 1.05-1.09. My GFR has decreased from 67 to 57 in 1 year and my GFRAA has decreased from 78 to 66 in 1 year. Is it time for me to see a kidney specialist? I keep asking my primary but she doesn’t seem concerned. I would very much appreciate your opinion.

I am unable to make a specific diagnosis based on the information that you present. Your history of high blood pressure is a risk factor for chronic kidney disease (CKD), but I cannot make a specific diagnosis of CKD based … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Nephrologist

I have recently got my blood work done because of my Doctor’s concerns with pre-diabetes. It came back as pre-diabetes. But what concerned me is I had GFR of 57.35, CHLORIDE 109 and CREATINE 1. Should I be concerned with kidney disease as well? I have high blood pressure, Graves disease, and a blood disorder that leaves me anemic most of my life. I am 56 years old.

I do recommend that you have blood testing for serum creatinine and estimated glomerular filtration rate (eGFR) and urine testing for protein, blood, and infection at least on an annual basis. I am unable to make a specific diagnosis at … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diabetes, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Serum Creatinine

I have kidney disease stage 3 but l see another doctor. He is saying it’s normal. Also, can l take bishop roll tablets? Thank you.

I am not able to make a specific diagnosis based on the information that you present. I do not know what “bishop roll” tablets are. I have never heard of these tablets.

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions