Category Archives: GFR

Good day Doctor. I am 42 years old, 190 cm tall and 82 Kg. My serum creatinine has been changing between 1.19 and 1.36 mg/dl for the last two years. No diabetes, blood pressure 120/70 in the morning, 130/80 before going to bed. Kidney ultrasonography shows everything OK. ACR is 1.4 mg/g. I was diagnosed with CKD stage 2, with a non specified origin. Any advice about which test should I take to know what exactly is wrong with my renal function and what should I do to avoid further damage? Thank you.

I cannot identify the basis of your diagnosis of Stage 2 chronic kidney disease. You will need to clarify this with the physician who made this diagnosis. In some cases, the only way to definitively establish a diagnosis of kidney … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney Biopsy, Kidney-Related Health Questions

Hi. I just received my blood test back and have a BUN level reading of 32 and a creatinine level of 1.25. I am 63 years of age, pre-diabetic, and overweight. Does this mean I have kidney disease?

The information that you provide suggests that you may have kidney disease. I suggest that you have a urine test for blood, protein and infection in addition to the testing that you describe. You can then use our estimated glomerular … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions

My wife’s last blood test shows she has an eGFR of 36. Her doctor said let’s wait and see what the next one says. Is he right?

I am unable to provide a specific diagnosis based on the information that you present. The estimated glomerular filtration rate (eGFR) that you provide would be abnormal for your wife, but I cannot tell is this is acute kidney injury … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions

My GFR is 52. When should I see a specialist instead of my primary care doctor?

In general, I have advocated for seeing a nephrologist if your primary care physician does not know the cause of your chronic kidney disease (CKD), is unsure about the treatment of your CKD, or the estimated glomerular filtration rate (eGFR) … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Nephrologist

Hello Dr., I am a kidney donor and a 67 year old white male. What should my GFR be? Thank you!

If you donated a kidney to someone for transplantation, your estimated glomerular filtration rate (eGFR) should be around 50% of normal. A normal eGFR is between 100 and 120 milliliters per minute per 1.73 meters squared. However, everyone loses kidney … Continue reading

Posted in Ask the Doctor, Donation, GFR, Kidney-Related Health Questions, Living Donation, Nephrectomy / One kidney, Transplantation

I am a diabetic and have been for 43 years. My question is, when should I see a kidney doctor for my kidneys? My creatinine is 1.6. My gfr is 31 and my bun is normal. I don’t have any health issues.

In general, I recommend that patients see a nephrologist if their estimated glomerular filtration rate (eGFR) is less than 30 milliliters per minute per 1.73 meters squared. You are very near this threshold. I recommend that you have urine testing … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions, Nephrologist

Blood Pressure 130/90 without medicine, ESR 28, Serum Uric acid 8.4, LDL 144 bilurubin total 1.4, ALT (SGPT) serum 45. Age 51 yrs. Does this indicate any renal disorder?

I do not identify any kidney disease based on the information that you present. The Uric Acid test is mildly elevated and this can be seen in patients with chronic kidney disease (CKD). In order to diagnose CKD you will … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Serum Creatinine

Hello Dr. Spry, This is follow-up to my question: “Is it possible that I could stay at “17” for many months or even several years or am I being just overly optimistic?” You really did not address this. Can I correctly assume there is not a simple response to this question?

Unfortunately, there is no way to know. I do not know why your estimated glomerular filtration rate (eGFR) dropped so fast in one year. This is unusual. Possibilities include lab error, use of non-steroidal anti-inflammatory drugs (NSAID’s), an episode of … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease

Hello Dr. Spry: I am a 79 year old Caucasian male. I have stage 4 Polycystic (PKD1) Kidney disease. I have been monitoring my steady eGFR decline for the past 3 years. In 2/8/17 my Creatinine was 1.83, eGFR 35. As of 9/18/19 my Creatinine was 3.30, eGFR 17. Over that time frame, slightly more than 31 months, my decline was 18. Obviously, quite a substantial loss. For the past 8 months (9/18/19-5/18/20) my eGFR has stabilized at 17, Creatinine 3.23. To me that is good news, no improvement but no deterioration either. Is it possible I could stay at “17” for many months or even several years or am I being just overly optimistic? I take Losartan to control BP, systolic is 126, non smoker, no diabetes, watch my sodium intake (do not own a salt shaker), and exercise regularly. Thank You.

I agree with you that you had a substantial loss of kidney function from 2017 to 2019. That is somewhat atypical for polycystic kidney disease (PCKD). Usually there is a slow steady loss of kidney function in the range of … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions, Polycystic Kidney Disease

Hello, Dr. I am a 25 year old white male. I was diagnosed with Hypertension 7 years ago, it has been treated ever since. On September 18, 2019, my Serum Creatinine was 1.26. I have not gained weight since then, just in case. On January 31, 2020, it was 1.42. Now (May 18, 2020) it’s 1.57. Since I am hypertensive, my Primary Doctor told me I have CKD. I do not have proteinuria yet. I calculated the rate of increase (of creatinine) per month from the first to second date and from the second to third date. It seems to be going slightly faster now than it did last year. Based on the current rate, my creatinine will be around 2.60 in 2 years. Is there a formula or a way to measure GFR decline and estimate future values? Will my GFR keep lowering at the current rate or will it get worse (faster)?

Your historical kidney function tests are the best way to estimate future reductions in kidney function. The exception to this rule is that if your blood pressure comes under better control, you limit your salt intake, don’t smoke and maintain … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions