Category Archives: GFR

Left kidney has angiomyolipoma near urinary tract. Creatinine level 1.10, GFR Non African level 52 ml. Multi benign cysts as well. Next step?

There is no treatment for an angiomyolipoma and all that can be done is to observe for any bleeding.  Benign cysts also do not require any treatment.  Your estimated glomerular filtration rate (eGFR) may indicate early Stage 3a chronic kidney … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney Cysts, Kidney-Related Health Questions

I have just posted my question yesterday and you told me that all the sympstoms I stated seems to be not related with CKD as CKD Stage 3 usually doesn’t have any symptoms yet. He has undergone kidney biopsy last December and we are told by the doctors that he has CKD Stage 3 and only 48% of his kidneys is working. As you have said that it may imply other severe kidney diseases, why is it that the biopsy detected that he has CKD? Thank you.

The kidney biopsy is the definitive way to diagnose chronic kidney disease (CKD) and tells you what disease process is causing the kidney damage.  The Stage of CKD is determined by measurement of a glomerular filtration rate (eGFR) and performance … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney Biopsy, Kidney-Related Health Questions, Nephrotic Syndrome, Symptoms and Side Effects, Urinary Tract Infection/Pyelonephritis, Urological Issues

Hi. I have a heart disease (ascending aorta aneurysm, BVD, mild to moderate AI, trace mitral regurgitation, mild tricuspid regurgitation), I get labs drawn every 6 months. My labs 11 Sept 2018 showed: Urea Nitrogen 22, CO2 23, anion gap 14, creatinine 0.9, and my egfr 76. Labs 19 September 2019 showed; Urea Nitrogen 15, CO2 21, Anion gap 18, creatinine 1, and egfr >60. Now on October 22nd, they were: Urea Nitrogen 20, CO2 22, anion gap 16, creatinine 1.1, and my egfr 56. My question is; is it normal that my egfr would drop that much in a year? Could this be because of my heart? My primary care doctor always brush it off saying I’m likely dehydrated! But, I’m drinking over a gallon of water a day. Should I be concern over these lab results?

The combination of heart disease and chronic kidney disease (CKD) is a difficult situation.  It can be true that heart disease affects the kidney but it can also be true that kidney disease affects the heart.  I can only suggest … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Serum Creatinine

Hi Dr Spry, thank for your assistance on this website. I am a bit confused with regards to blood serum creatinine and how it relates to GFR. I am a non black Caucasian with a naturally muscular build. I consistently run/walk 14-18 miles per week and have no health issues with the exception of slighly elevated cholestorol which I control with diet and exercise. My height is 66″ with a weight of 185 lbs. In October 2017 I did a blood test and my creatinine levels were 1.39. Since then however I have had 2 blood tests and on both my creatinine levels were 1.05. Is this considered high for my age and body type? My doctor has said after both tests showing creatinine of 1.05 that I do not show any signs of kidney disease. However, when I compute these on the GFR calculator it says my GFR 93. But yet when I apply the body surface adjustment it says my GFR is 104. Since I am not obese which of these results should I regard as accurate?

When we discuss populations of individuals, the normals must be expressed in terms that allow comparison of one individual to the next.  The serum creatinine is inversely proportional to the glomerular filtration rate (GFR) and directly proportional to the muscle … Continue reading

Posted in Ask the Doctor, GFR, Kidney-Related Health Questions, Serum Creatinine

I AM 74. GFR was 25, creatinine 2.64. I was told to increase liquid intake to 2 liters per day. Tested again in 30 days. Results Gfr dropped to 21, creatinine rose to 3.16. Bun level is 35. I have been told to drink more water. Can I be drinking too much?

Drinking too much water would be unlikely to raise the serum creatinine and reduce the estimated glomerular filtration rate (eGFR).  I would suggest that you discuss these results with your physician.

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Serum Creatinine

DEAR DR. THANK YOU FOR PREVIOUS ANSWER. THIS TIME IS JUST YOUR OPINION, NOT A CONSULTATION. IT IS JUST STRANGE THAT (AM STAGE 3 pkd AT THIS MOMENT), MY GFR GOES UP AND DOWN WITH THE CREATININE. WHY? MAYBE WHAT WAS EATING? WATER? MEDICINE? I AM TAKING THE FOLLOWING: LOTREL 5-10 BEDTIME-LOTREL 2.5 10 MORNING-DIAZEPAM WHEN NEED-SINTROYD 80 MG-VENTOLIN FOR MY ASTHMA. COULD BE ONE OF THESE FACTOR? THANK YOU

The variability of the serum creatinine and the estimated glomerular filtration rate (eGFR) is just a natural variation that occurs from day to day and also is the result of normal laboratory variation.  This variation is not clinically significant and … Continue reading

Posted in Ask the Doctor, GFR, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function, Serum Creatinine

My CT scan in 2016 incidentally showed a developmental anomaly of a circumaortic left renal vein. Also the scan showed that I have a couple of small unidentifiable but “typically benign” lesions (one on each kidney). My recent GFR was 57 (I am having it retested to confirm the accuracy of the number). My question: is it possible for a circumaortic left renal vein to cause CKD? I also feel that I should have another CT scan since it has been three years since my scan. Thank you

The renal vein that encircles the aorta does not cause any kidney disease.  There is a syndrome of having the left renal vein trapped between the aorta and the superior mesenteric artery that is associated with blood in the urine … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hematuria, Kidney-Related Health Questions

I had my yearly physical 2 months ago. My RBC was 6 -below 20 as normal, protein in urine was 50 – below 20 as normal. I was dehydrated during testing. I was retested a month later. The BUN was 10, creatinine-0.8, albumin 3.9. I also had a 24 hour urine test. I didn’t eat any protein a couple of days prior to the test. Did I cause an inaccurate result because of not eating protein? Total protein was 7.2, mid normal range. Still having some foamy urine, mainly in the morning. Having some sensations in the right kidney area. Should I retest 24 hour urine and eat normal protein? My 24 hour results were below 5, unable to calculate the 24 hour UP as the random urine protein is less than the lower technical limit. Thanks for your help

Avoiding protein intake will have almost no impact on urine protein.  Eating a low protein diet without red meat might cause the serum creatinine to be a little lower than it might otherwise be and this would result in a … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diet/Nutrition, GFR, Kidney-Related Health Questions, Proteinuria

Hello, My doctor is telling me I don’t have anything to worry about, but I would like to see what you think. My doctor says there is no worry about these numbers because “the existing controversy of using only eGFR and Creatinine levels as markers for staging of CKD and that without evidence of protein, blood or possibly glucose in his urine that attempting to stage CKD is futile.” I am very worried. I am a 50 Year old white male currently stationed at Fort Leavenworth, Kansas. I take 10 Mg of Lisinopril for High Blood pressure (started March 2019) and 10mg of Lipitor for cholesterol (started September 2019), height 5’9″, weight 178lbs. I have never had any health problems before this year. My current lab tests results are below.C-Reactive Protein <0.20 GFR Stats for past 2 years. March 2017 = 68.8 May 2019 = 67.18 September 2019 = 66.0713 October 2019 = 55.7528 (10.3185 point drop from previous month) He told me about the existing controversy of using only eGFR and Creatinine levels as markers for staging of CKD and that without evidence of protein, blood or possibly glucose in his urine that attempting to stage CKD is futile. Urinalysis Results – October 2019 "Urinalysis W/Reflex Microscopic+Culture" Test Name Appearance – Clear Albumin – 4.5 Bilirubin – Negative Blood – Negative Color – Yellow Glucose – Negative Ketones – Negative Leukocyte Esterase – Negative Nitrite – Negative pH – 5.5 Potassium – 4.4 Protein – Negative Specific Gravity – 1.01 Urobilinogen – 0.2 Chem 14 w/eGFR (Plasma) Results – October 2019 Albumin – 4.5 Bilirubin -1.0 Calcium – 9.3 Carbon Dioxide – 24.3 Chloride – 104 Creatinine 1.45 Higher Than Normal Glucose 99.0 Alkaline Phosphatase 92 Potassium 4.4 Protein – 8.60 Higher Than Normal Sodium 139 Alanine Aminotransferase 28 Aspartate Aminotransferase 17 Urea Nitrogen 17 GFR Non-Black 55.7528 Lower Than Normal Please let let me know what I can do if anything. Thanks

High blood pressure is among the most common causes of chronic kidney disease (CKD).  The single test that you mention with an estimated glomerular filtration rate (eGFR) of 55.7 milliliters per minute per 1.73 meters squared seems to be an … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Treatments

Hi Doc. My brother just got diagnosed with stage 5 renal failure after pneumonia Creatinine of 9.12 and eGFR of 7mls/min. After recovering we did creatinine recheck and it’s 4.5 eGFR of 17. Should we still go ahead with dialysis or try home remedies 1st to improve the condition. Is the condition reversible at this stage? Thank you!

I do not know of any home remedies that reverse acute kidney injury.  From what you describe, your brother may have acute kidney injury but I cannot make a specific diagnosis as to the cause, based on the information that … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Dialysis, GFR, Kidney-Related Health Questions, Treatments