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Category Archives: IgA Nephropathy/IgA Dominant Glomerulonephritis
Dear Doctor and entire team, first of all I thank you for devoting your time and services for your patients. Please advise me regarding stem cell therapy for stage 5 CKD due to IgA Nephropathy? Where is Stem cell therapy for CKD available even if it’s in trials? How much will it cost to do the stem cell therapy? Thank you.
There are no stem cell treatments that are approved by the Food and Drug Administration (FDA) for any form of kidney disease. There is a web site where you can search for stem cell treatment trials. I went to the … Continue reading →
Is B12 supplement safe for IGA stage 4 if you have very low levels of it (179 and the range is 250-1200)?
Yes, Vitamin B 12 supplement is safe for patients with chronic kidney disease (CKD). Even with advanced kidney disease and you take too much B 12 supplement, the kidney can still eliminate any vitamin B 12 that your body does … Continue reading →
I have IGA nephropathy with a gfr 51. I was diagnosed over 32 years ago so I feel very blessed. However I have peripheral neuropathy which has progressively worsened during this time. I have been evaluated by several neurologists and as you are aware very little can be done to alleviate the progressive pain. I have been under the impression that with IGA that neuropathy is is not commonly found as one of the symptoms. At this point I have been diagnosed with idiopathic neuropathy. It would be he helpful to know if my neuropathy is related to my kidney disease. Thank you for sharing your expertise with so many who suffer with chronic kidney disease.
I am unaware of any association of idiopathic Immunoglobulin A (IgA) nephropathy and peripheral neuropathy. Peripheral neuropathy may be seen with advanced kidney disease (usually Stage 4 or 5 with estimated glomerular filtration rates of less than 30 milliliters per … Continue reading →
Hi. I am 31 F. I have been feeling rotten recent month. Then had an infection so had my bloods done. They showed an iron deficiency, anemia as well as infection. My Hgb was 10.3 ferritin 6.9. I have been taking oral iron before this too. My creatinine was 1.61, Ur 11.7, eGFR 40. Thinking is likely to be IgA nephopathy. They thought would be periods, although mine are light and short. Last had check, last year my Hgb was 13.5. Do you think it is relevant to the kidney check and what options are there to improve the anemia? Thanks.
Kidney disease and anemia commonly occur together. The kidney is responsible for making a hormone known as erythropoietin. This hormone helps to make red blood cells. In patients with acute or chronic kidney disease, anemia is very common. It is … Continue reading →
You will need to know your serum creatinine and then use this value to calculate your estimated glomerular filtration rate (eGFR). The eGFR is then used to categorize your stage of chronic kidney disease (CKD). You can review the calculation … Continue reading →
My friend has Berger’s and I was curious about what would happen if someone with IgA deficient blood gave him a transfusion? Or transplant? Would it decrease the build up in his own kidneys ‘naturally’? I really am curious if this is an avenue researched have looked into… We both grew up in the same environmental area and attended the same school. I’ve always felt like I should donate my kidney, but my doctor has said not because of the IgA issue I have. I have IgA deficient, O positive blood.
The problem in IgA nephropathy (which is also known as Berger’s Disease) has to do with the abnormal way of making IgA so that the molecule is damaged. Someone with IgA nephropathy has a tendency to make abnormal IgA molecules … Continue reading →
I wanted to ask your opinion on the supplements acetyl l carnitine and alpha lipoic acid used for pain control in those with neuropathy. I have IGA neuropathy and my last GFR (Oct. 2018) was 51.
Carnitine has been studied in the treatment of anemia associated with dialysis patients. Alpha lipoic acid has been advocated for the treatment of painful neuropathy associated with diabetes. I am not aware of any studies done with either of these … Continue reading →
I am suffering from IgA nephropathy since I was 17, now I am 35, currently in stage 3 CKD. I am currently taking omega 3 fatty acids and Losartan 50mg. Due to shortness of breath and lack of sleep, my doctor has advised to stop Losartan. So, I am now only taking omega 3. Could you please advise on this as this is the first time I am stopping Losartan over these years? The blood tests are Albumin ++ and creatinine 1.4.
The standard treatment of IgA nephropathy has been to use ACE inhibitors or ARB agents with or without fish oil. Losartan is an ARB agent. In some cases, prednisone and immunosuppression has been recommended but there are no clear cut … Continue reading →
Doctor, my wife is diagnosed with IgA +3 Disease and advised to take steroids. Her current B/P is 140/90 and proteinuria 4+. Please advise whether steroids are must to take or we can go for alternative medicines?
The use of blood pressure agents such as ACE-inhibitors and ARB agents are most commonly recommeded in patients with Immunoglobuliln A (IgA) nephropathy. Corticosteroids, such as Prednisone or Dexamethasone are also commonly used depending on characteristics found on the kidney … Continue reading →
I a 48 year old caucasian male, diagnosed with Stage 3 CKD in 2017, biopsy confirmed IgAN in January of this year, was started on Prednisone and SoluMedrol for 6 months. With two more weeks of Prednisone treatment. For the first time in 18 months I have no Hemoglobin or RBC in my urine. However, my creatinine level has remained around 1.6 and my GFR is 47, it was 46 at the beginning of treatment in January. Is the resolving of hematuria (given no appreciable improvement in GFR) reason to celebrate? Or with no improvement in GFR has Prednisone not worked for me? I have not had an issue spilling protein, until I convinced my nephrologist to allow me to suspend Lisinopril for 2 months. Once I restarted the 10mg of Lisinopril my protein spillage resolved. I have read that hematuria and proteinuria are bad prognostic predictors for progression of IgAN towards ESRD. I remain hopeful with these resolved, however am confused why my eGFR or creatinine are not also showing improvement.
In the case of glomerulonephritis and in the specific case of Immunoglobulin A nephropathy (IgA nephropathy), once glomeruli have been destroyed by disease, it may not be possible to repair old ones and it is NOT possible to build new … Continue reading →