Category Archives: IgA Nephropathy/IgA Dominant Glomerulonephritis

Do you have any insight on Loin Pain Hematuria and its correlations with IGa Nephropathy?

Loin Pain Hematuria syndrome is a collection of symptoms that include microscopic and rare macroscopic blood in the urine (hematuria) associated with bouts of flank and back pain but the kidney is normal on biopsy. With IgA nephropathy, blood can … Continue reading

Posted in Ask the Doctor, Hematuria, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions, Proteinuria

I have just been diagnosed with IgA nephropathy (although they have not yet confirmed the diagnosis via biopsy). Could you let me know what the normal prognosis is?

The only way to make a specific diagnosis of IgA nephropathy is to perform a kidney biopsy.  IgA nephropathy has many different clinical courses and manifestations.  The biopsy information also results in important features that suggest prognosis.  Hence, if a … Continue reading

Posted in Ask the Doctor, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

I am a relatively healthy 30 year-old female, who was randomly sent to the hospital in September to discover I had a kidney condition. In the hospital, my kidney function was about 10-15%. After biopsy, it was decided that I have IgA nephropathy. Since then, my kidney function has been testing normal, however I tend to feel fatigued, get headaches (migraines), trouble concentrating, sometimes nauseous or lack of appetite, also back aches. Overall I just don’t feel “right.” I was put on Benazepril, but stopped because my blood pressure has been normal. I have been seeing a nephrologist, nutritionist, and my primary care physician, all of which say different things. Do you recommend any other tests or procedures to have done to dive a little deeper?

IgA nephropathy is a relatively common kidney disease that commonly results in blood and protein showing up in the urine.  Benazepril or other ACE-inhibitors are commonly used to treat the disease.  The Benazepril or other ACE-inhibitors are used even if … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Medication and Kidney Function

I have IgA nephropathy stage 3A. I have been prescribed by a specialist Diclofenac Sodium Topical 1% gel for severe burning pain in my feet caused by neuropathy.  I am not sure what it contains but I think it is in the NSAID family.  I am well aware of your guidance not to use these types of pain medications but I wonder if a topical application would be any safer

The topical use of non-steroidal anti-inflammatory drugs (NSAID’s) such as Diclofenac is generally considered safe for patients with chronic kidney disease (CKD).  The amount that is absorbed into the blood is very small when used topically.

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Medication and Kidney Disease

I have been suffering IgA nephropathy about 30years. I am now 49 years woman. My disease is not severe, just protein and hematuria in my urine. I have ACE medicine, for keeping my blood pressure solid because I have no high pressure. I have read studies where it’s said, that they have found diet without gluten (maybe dairy and red meat too) has been useful and protein has decreased and the glomerulus has gotten better. Is it worth it to leave gluten and maybe dairy and red meat out on diet to help my kidneys?

There are many theories about the cause of IgA nephropathy that include dietary causes such as gluten and other foods in the diet (as you mention). These remain theories because no study has yet shown that adjusting the diet in … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Proteinuria

I was diagnosed with Chronic Hep B over 16 years now. But no treatment of any sort has been taking because of no incident. I have to do LFT and kidney function test which I recently did and the result showed that my plasma creatinine was high 145mmol/L and total Bilirubin 31mmol/l. I am already in consultation with a gastroenterologist who asked me to do more test, which I have done and waiting for result. (Viral load, serum alpha fp, Hep BeAg and Hep BeAb). I commenced Livolyn Forte yesterday while I wait for the outcome of the results. So what treatment do you think I should start with because of the high creatinine. Thank you.

Chronic hepatitis B is associated with several kidney diseases including cryoglobulinemia, vasculitis, IgA nephropathy, membranous nephropathy and membranoproliferative glomerulonephritis. I am unable to make a specific diagnosis based on the information that you present. I am unable to recommend treatment … Continue reading

Posted in Ask the Doctor, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

My brother 24 years old is diagnosed with IGA Nephropathy with Cresents with Sclerosis with Hypertension on 19 july 2017. He is on Wysolone 90mg OD since two and half months (20 july 2017 -present),Telmisartan 40mg OD (22 sep 2017-present), Cilnix 10mg OD, Metcy 100mg OD ,Moxovas 0.2mg OD ,Lasix 20mg OD, Renosave OD, Sobisis forte TDS, Atorlip-f 20mg, Hosit OD (3 july 2017-present), corcal 500mg BD. His creatinine is 3.09 and 24 hr urine protein is 1.6 gm (20 sep 2017)which was 4.64 and 4gm at the time of biopsy. All RFT test with in normal range. His BP is within 130/90 (measure 3 times a day). Will he need dialysis and what is the prognosis. What will be line of treatment in future?

I am unable to provide a prognosis based on the information that you present. IgA nephropathy has a very variable clinical course and is different from one individual to the next. The biopsy that you mention suggests very aggressive disease … Continue reading

Posted in Ask the Doctor, Dialysis, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

Micro-Chinese Medicine Osmotherapy have you heard of any positive real results under this treatment for patients with Iga Nephropathy? How does Cyclophosphamide help in reverting IgA Nephropathy?

I am not aware of any successful treatment of IgA nephropathy with Chinese Medicine Osmotherapy.  I believe this therapy is of no benefit.  Cyclophosphamide is a very potent immunosuppressive therapy that must be used with caution.  It is a cancer … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Symptoms and Side Effects, Treatments

Last December, my creative creatinine level was 2.85. In July it was 4.01! I’m really scared. My Nephrologist said my nephropathy is getting worse. That is an understatement. I had a biopsy a year ago. The diagnosis was stage 4 IgA. Been on a self directed strict diet, restricting my intake of protein, and foods high in salt, and phosphorous. Was not overweight, but lost 28 lbs. Am always tired, but walk about 30 minutes every other day. I’m 41 year old Filippine female. My husband is a medical professional and feels that maybe now is the time to take a more aggressive approach. I’ve been taking 9,000 units of fish oil for over a year. Cyclophosamide along with corticosteroids and a removal of my tonsils should put me in remission.

I am not able to give medical advice without performing a complete history and physical examination.  It is best for you to consult with your nephrologist in the Philippines.    IgA nephropathy is a notoriously difficult disease to treat.  

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects

I have some kidney failure and blood and protein in urine (IGA nephropathy). Now, I am getting treatment and drugs chart are shown below. 01st month 48mg methylprednisolone, 25mg Repace, 430mg Kalzana, 150mg Ranitidine. 02nd month 32mg methylprednisolone, 25mg Repace, 430mg Kalzana, 150mg Ranitidine. 03rd month-currently (from2017.05.29) 24mg methylprednisolone (one week), 16mg methylprednisolone (two weeks), 25mg Repace, 430mg Kalzana, 150mg Ranitidine. Doctor, please tell me: 1. Are my drugs chart correct or not? 2. What is the current situation of my illness? 3. Can I fully solve my problem? 4. What should I do in future?

IgA nephropathy (also known as Berger’s Disease) is a highly variable disease and does not have a consistent clinical course.  In most patients, it is associated with blood and protein in the urine.  The treatment that you mention with methylprednisolone … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions