Category Archives: IgA Nephropathy/IgA Dominant Glomerulonephritis

I have been suffering IgA nephropathy about 30years. I am now 49 years woman. My disease is not severe, just protein and hematuria in my urine. I have ACE medicine, for keeping my blood pressure solid because I have no high pressure. I have read studies where it’s said, that they have found diet without gluten (maybe dairy and red meat too) has been useful and protein has decreased and the glomerulus has gotten better. Is it worth it to leave gluten and maybe dairy and red meat out on diet to help my kidneys?

There are many theories about the cause of IgA nephropathy that include dietary causes such as gluten and other foods in the diet (as you mention). These remain theories because no study has yet shown that adjusting the diet in … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Proteinuria

I was diagnosed with Chronic Hep B over 16 years now. But no treatment of any sort has been taking because of no incident. I have to do LFT and kidney function test which I recently did and the result showed that my plasma creatinine was high 145mmol/L and total Bilirubin 31mmol/l. I am already in consultation with a gastroenterologist who asked me to do more test, which I have done and waiting for result. (Viral load, serum alpha fp, Hep BeAg and Hep BeAb). I commenced Livolyn Forte yesterday while I wait for the outcome of the results. So what treatment do you think I should start with because of the high creatinine. Thank you.

Chronic hepatitis B is associated with several kidney diseases including cryoglobulinemia, vasculitis, IgA nephropathy, membranous nephropathy and membranoproliferative glomerulonephritis. I am unable to make a specific diagnosis based on the information that you present. I am unable to recommend treatment … Continue reading

Posted in Ask the Doctor, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

My brother 24 years old is diagnosed with IGA Nephropathy with Cresents with Sclerosis with Hypertension on 19 july 2017. He is on Wysolone 90mg OD since two and half months (20 july 2017 -present),Telmisartan 40mg OD (22 sep 2017-present), Cilnix 10mg OD, Metcy 100mg OD ,Moxovas 0.2mg OD ,Lasix 20mg OD, Renosave OD, Sobisis forte TDS, Atorlip-f 20mg, Hosit OD (3 july 2017-present), corcal 500mg BD. His creatinine is 3.09 and 24 hr urine protein is 1.6 gm (20 sep 2017)which was 4.64 and 4gm at the time of biopsy. All RFT test with in normal range. His BP is within 130/90 (measure 3 times a day). Will he need dialysis and what is the prognosis. What will be line of treatment in future?

I am unable to provide a prognosis based on the information that you present. IgA nephropathy has a very variable clinical course and is different from one individual to the next. The biopsy that you mention suggests very aggressive disease … Continue reading

Posted in Ask the Doctor, Dialysis, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

Micro-Chinese Medicine Osmotherapy have you heard of any positive real results under this treatment for patients with Iga Nephropathy? How does Cyclophosphamide help in reverting IgA Nephropathy?

I am not aware of any successful treatment of IgA nephropathy with Chinese Medicine Osmotherapy.  I believe this therapy is of no benefit.  Cyclophosphamide is a very potent immunosuppressive therapy that must be used with caution.  It is a cancer … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Symptoms and Side Effects, Treatments

Last December, my creative creatinine level was 2.85. In July it was 4.01! I’m really scared. My Nephrologist said my nephropathy is getting worse. That is an understatement. I had a biopsy a year ago. The diagnosis was stage 4 IgA. Been on a self directed strict diet, restricting my intake of protein, and foods high in salt, and phosphorous. Was not overweight, but lost 28 lbs. Am always tired, but walk about 30 minutes every other day. I’m 41 year old Filippine female. My husband is a medical professional and feels that maybe now is the time to take a more aggressive approach. I’ve been taking 9,000 units of fish oil for over a year. Cyclophosamide along with corticosteroids and a removal of my tonsils should put me in remission.

I am not able to give medical advice without performing a complete history and physical examination.  It is best for you to consult with your nephrologist in the Philippines.    IgA nephropathy is a notoriously difficult disease to treat.  

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects

I have some kidney failure and blood and protein in urine (IGA nephropathy). Now, I am getting treatment and drugs chart are shown below. 01st month 48mg methylprednisolone, 25mg Repace, 430mg Kalzana, 150mg Ranitidine. 02nd month 32mg methylprednisolone, 25mg Repace, 430mg Kalzana, 150mg Ranitidine. 03rd month-currently (from2017.05.29) 24mg methylprednisolone (one week), 16mg methylprednisolone (two weeks), 25mg Repace, 430mg Kalzana, 150mg Ranitidine. Doctor, please tell me: 1. Are my drugs chart correct or not? 2. What is the current situation of my illness? 3. Can I fully solve my problem? 4. What should I do in future?

IgA nephropathy (also known as Berger’s Disease) is a highly variable disease and does not have a consistent clinical course.  In most patients, it is associated with blood and protein in the urine.  The treatment that you mention with methylprednisolone … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions

I am male, 30 years old and I have Proteinuria. Doctors suspect some kind of Glomerulonephritis. One doctor thinks is IgA Nephropathy. And I am really confused and worried. I decided to do a biopsy to find out in about a month from now. The laboratory results are confusing me a bit as they use different measurements. All are urine test results here. January 2017: Urinary Micro Albumin: 1132 mg/L Urinary Creatinine: 1.25 gm/L Albumin Creatinine Ratio (ACR) 905.0 mg/gm February 2017: Urinary Micro Albumin: 590 mg/L Urinary Creatinine: 0.60 gm/L Albumin Creatinine Ratio (ACR) 983.0 mg/gm May 2017: Urinary Albumin: 109.2 mg/dL Urinary Creatinine: 0.08 g/dL Albumin Creatinine Ratio (ACR) 1365 mg/g (Different laboratoy than the 2 previous) I will appreciate a lot if you kindly would give me your feedback.

The only result that you quote consistently is the urinary albumin to creatinine ratios.  The other results reflect the concentration of the urine and are not significant.  The urinary albumin to creatinine ratios are between 905 and 1365.  These numbers … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Hydronephrosis and Hydroureter, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist

My friend was diagnosed with IgA nephropathy stage 3 about 1 yr ago. His current function is 24, taking predisone along with hypertension medication. What is his kidney risk for failure? He is 68 yrs old. Thank you.

I am unable to provide a prognosis without performing a complete history and physical examination.  The best person to ask this is his nephrologist, who knows his prior history and can perform a physical examination. For more information on IgA … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Laboratory Testing, Treatments

Hi Doctor, My partner was diagnosed 5 years ago, at the age of 26, with a rare Kidney disease called mesangial capillary glomerulonephritis. He has been on steroid treatment and also cholesterol, blood pressure and other pills. He has suffered with many side effects including depression, mood swings, frequency of urination, dizziness, blurred vision and most recently the beginnings of osteoporosis. I have heard of Chinese Medicine Osmotherapy and read about some studies on www.ncbi.nlm.nih.gov and it seems very effective in treating patients with IgA nephropathy. I was wondering if you think this might work for my partner too? and whether it could be used in conjunction with his current medications? My second question is how likely do you think it would be for us to pass this disease down to a child? Thank you for any help you might give us… I worry about our future family and hope that someone will find a cure soon.

Mesangiocapillary glomerulonephritis (MCGN) is an uncommon kidney disease.  There are many different forms of MCGN that have been described.  Chinese medical osmotherapy is of no benefit in any kidney disease that I am aware. I cannot comment on whether you … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Glomerulonephritis, Hypertension/High Blood Pressure, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Nephrologist, Pregnancy / Kids, Symptoms and Side Effects, Treatments

I have been diagnosed with IgA nephropathy and is in stage 3 CKD. My question is related to diet. I have observed from experience that if I follow a low protein diet, my egfr and creatinine seems to be in better level. When I increase food intake there is a decrease in egfr and increase in creatinine levels. My nephrologist insists not to worry about diet or protein at this stage. Is it better to take less food and be underweight or is it better to take enough food and worse the blood results?

I agree with your physician.  I am not a fan of low protein diets.  This can lead to malnutrition which can have other ill effects on your body.  I suggest that you follow a low salt DASH diet.  You can … Continue reading

Posted in Chronic Kidney Disease, Diet/Nutrition, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney-Related Health Questions, Treatments