Category Archives: Kidney Biopsy

Hello. I have had blood in my urine for a couple of years now. They did a culture and all was fine. I then got a kidney ultrasound and it was fine as well. My kidney function continues to decline and now my BUN is elevated and my anion gap is low. I don’t have any swelling, pain etc. Also my folic acid is high. Any ideas? Thank you.

In some cases, when a diagnosis is not evident and kidney function has started to decline, a kidney biopsy may be necessary in order to know what disease you are dealing with and see if any treatment is available.  I … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

I have a question regarding FSGS. Recently a dear person to me told me that she was diagnosed with MCD when she was 6 years old ( biopsy was taken at that time). Few years later she mentioned that another biopsy was taken which showed FSGS. Ever since she was followed up by nephrologists and was on steroids and in 2010 she was on cellcept until she stopped both steroids and cellcept in 2016. She had testing done and her recent test shows only an elevated ACR of 67 which I’m assuming to be subnephrotic range. All her kidney functions and ultrasounds were normal and so for the past 26 years she has had this condition and kidney function seems fine. My question is what are the chances of her going into ESRD and needing dialysis? I know it is difficult to speculate but given a history of what I’m guessing a stable partial remission FSGS what are the likelyhood of needing dialysis down the road? Do all fsgs patients end up on dialysis? Thank you

Focal and segmental glomerulosclerosis (FSGS) has many different courses and many different presentations. There is not just one clinical course for all patients with FSGS. In fact, minimal change disease (MCD) has often been found to evolve into FSGS when … Continue reading

Posted in Ask the Doctor, FSGS, Kidney Biopsy, Kidney-Related Health Questions, Minimal Change Disease

I have stage 3 kidney disease. I have several tests and still no clue as to why I have at least 2000 mg of protein spewing into my urine. What other reasons are there? I’m 40 and have children. Back in 2016, it was 42, didn’t know and now it is 33. I don’t want to die. I have a biopsy scheduled in a few weeks. No family problems, no high blood pressure or diabetes. Been loosing weight. Drinking lots of water. I am working with specialist but need more answers, Please.

The kidney biopsy should supply the answers you are seeking. There are forms of kidney disease, including glomerulonephritis, that can only be determined with a kidney biopsy. There are no specific blood tests for glomerulonephritis and a biopsy must be … Continue reading

Posted in Ask the Doctor, Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions

I have been recently diagnosed with mild tubular atrophy and interstitial fibrosis (and stage 3 CKD) via a needle biopsy. The etiology is unknown- my nephrologist suspects its due to medication side effects since I do not have the many other conditions which may cause it. I was told to avoid certain medications like PPIs and NSAIDs. I am concerned that there is not a definite cause given. Knowing a specific cause can help me plan my lifestyle to hopefully avoid whatever has caused/contributed to it. I’d like to know if further tests might better define the cause. I am wondering if I should get a second opinion or what I should request of my current nephrologist. Any feedback is appreciated.

Interstitial nephritis is an uncommon cause of chronic kidney disease (CKD). A kidney biopsy is the definitive way to make a kidney diagnosis, so you have had the definitive test for kidney disease. There are many causes of interstitial nephritis, … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Gout, Kidney Biopsy, Kidney-Related Health Questions

Hi, I noticed bubbles in my urine in early April. I saw a doctor in mid April and have since found out that I have eGFR of 38. I had a 24 hour urine test done and my total protein was 7630. I have none of the typical pre-existing conditions – e.g. no diabetes, normal blood pressure. Other tests showed a very high level of inflammation and somewhat anemic. Neither my GP nor my nephrologist seems particularly concerned about my high protein. I have a kidney biopsy scheduled for next Thursday, and it will take another week before we get any results. I’m guessing nothing will happen for another month. I am very anxious that so much time is transpiring with such high protein in my urine and no treatment. It has been two months already. Does another month matter? Thank you.

The amount of protein in your urine is quite high. This amount is known as nephrotic range proteinuria. Any amount of protein that is greater than 3500 milligrams of protein per day is nephrotic range proteinuria. In this case, the … Continue reading

Posted in Ask the Doctor, Hypertension/High Blood Pressure, Kidney Biopsy, Kidney-Related Health Questions, Nephrotic Syndrome

Hi. I have high blood pressure and have been seeing a nephrologist for proteinuria. Recently my Dr said my protein levels in urine were extreme and there was also blood in the urine. She said my GFR and kidney function tests were ok. She has booked me for a renal biopsy. Why do I need a biopsy?

A kidney biopsy will provide a definitive diagnosis and will lead to proper treatment of your kidney disease. If you do not have any of the usual risk factors for kidney disease, and your urine is abnormal with blood and … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

Hello! I am a 61 y.o. female and have had blood in my urine going back to 2007. An ultrasound in 2015 showed mild kidney disease. I recently had another ultrasound after another UA showed a large amount of blood in my urine. No proteinuria. I have an eGFR of 56 -Stage 3a. I’m supposed to have a CT next week. My grandfather died at age 53 from kidney failure. My father had to go on dialysis in his mid-60’s and stopped after about 4-1/2 yrs. He died at age 69. With my family history, I am curious about my prognosis pertaining to how fast I may wind up at Stage 5. I am not overweight, no diabetes or high BP. Is there any way to predict this? Thank you.

I am not able to make a specific diagnosis or prognosis based on the information that you present.  I am not sure what is causing the blood in your urine or your kidney disease.  In some cases, such as this, … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

Do you have any insight on Loin Pain Hematuria and its correlations with IGa Nephropathy?

Loin Pain Hematuria syndrome is a collection of symptoms that include microscopic and rare macroscopic blood in the urine (hematuria) associated with bouts of flank and back pain but the kidney is normal on biopsy. With IgA nephropathy, blood can … Continue reading

Posted in Ask the Doctor, Hematuria, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions, Proteinuria

My family has a long history of kidney failure. In fact my mom is the 8th person in the family line that has been diagnosed with kidney failure. Her kidneys are currently working at 22%. The 7 other family members have been through dialysis and eventually having a kidney transplant. I am 34 years old and will be seeing the kidney doctor in April to look at my kidney function. At 34 years old my GFR is at 67. From the research I have done that seems to be low considering my age and health. All the doctors we have spoken to tell us this is not hereditary however seeing 8 family members deal with the same disease seems to tell us otherwise. We would be interested in possible clinical trials to look into our families kidney history.

I am not aware of any clinical trials that studies families with unknown kidney disease. It is most often necessary that a kidney biopsy has been done in one or more individuals in a family to confirm that the kidney … Continue reading

Posted in Ask the Doctor, Clinical Trials/Studies, Kidney Biopsy, Kidney-Related Health Questions

My renal function is deteriorating due to being a diabetic for a over 35 years, and has been recommended for a renal biopsy. However, without any indication that my consultant who referred me is leaving the hospital. He won’t be there to discuss the result afterward. I feel very much let down by the news. Wonder if I should go for the procedure at all.

I am not able to make a diagnostic recommendation without performing a complete history and physical examination.  If you have concerns about the kidney biopsy, I recommend that you again consult the nephrologist who will be taking the place of … Continue reading

Posted in Ask the Doctor, Diabetes, Kidney Biopsy, Kidney-Related Health Questions