Category Archives: Kidney Biopsy

Hello, Doctor. I am from Ethiopia. Yesterday, the doctors told me that I have a big kidney problems. So, I don‘t know what I should do? If you can, please say something?

Since you have been told that you have kidney disease, it is first important to know if this kidney disease is acute or chronic. Acute kidney disease or acute kidney injury, can generally be treated and may be reversed in … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions

Good afternoon Doctor, I am 37 years old and I live in Colombia I have an unspecified chronic kidney damage, I feel very bad since the nephrologist says that if I have a biopsy I can bleed because my kidneys are small, creatinine It is 2.40 I do not have diabetes or suffer from high blood pressure my bones if they hurt me a lot and there are days that I feel very tired I would like to know a treatment and what can I do Doctor please. Thanks from my heart.

If you have none of the usual risk factors for kidney disease, such as high blood pressure, diabetes, family history, or obesity, then a kidney biopsy may be the only way to tell you what your disease may be. In … Continue reading

Posted in Ask the Doctor, Diabetes, Hypertension/High Blood Pressure, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

My daughter is 22 yrs old and has had either a +1 or +2 protein and +1 to +3 blood in all of her urine tests since 2015. Had a cystoscopy done that showed nothing. Now she has a positive ANA titer of 1:1620, sed rate of 24, and c reactive protein of 1.22. White blood count of 11.2 Strong urge to urinate all the time but no infection. Not real obvious swelling but she complains of sore joints and she gets puffy under her eyes. Her total protein/creatinine ratio is 341.1 but her eGFR says >60. Rheumatologist ran 13 tubes of blood and she’s tested neg for all major autoimmune diseases. But there is obviously some type of inflammation issue going on somewhere in her body. Could all of her positive protein and blood urine tests be causing the positive ANA test? And should we be concerned that there is a kidney issue going on?

I am unable to provide a specific diagnosis based on the information that you present. In some cases a kidney biopsy is necessary to make a specific diagnosis of inflammation of the kidney. This could be some form of glomerulonephritis … Continue reading

Posted in Ask the Doctor, Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

Hello Doctor, I am age 39 years. I am living in Denmark from May 2015 but I am originally from India. My urine report says that I have protein in my urine. I have undergone 4 tests from May 2018 onwards till now. My father was having kidney disease and high blood pressure and he died to kidney failure at age of 78. My elder brother is of 49 years and both of his kidneys have failed and he is on dialysis from December 2016 onwards. This is the reason I am worried. I read on internet and found that protein in urine because kidney is unable to filter it out from blood. If protein in urine comes for 4 consecutive times at interval of each month, it means there is some problem with kidney. I also suffer from high blood pressure and I take following medicine every day once: 1. Tolura 80 mg (Telmisartan) 2. Simvastatin 40 mg. I was taking above medicine as advised by Indian doctor from 2013 onwards and doctor in Denmark continue the same medicine. Doctor in Denmark increased the dosage of Tolura from 40 to 80 from June 2018 onwards and told me that it will help kidney to work fine. I had a blood and Urine test today i.e. 15.08.2018. The report says that protein level have been increase from last time so increasing dosage from 40 to 80 mg is not helping. I believe there is something wrong with my kidney. I talked to my doctor here and they said that if protein level is 750 or above or it increase by 5 every year than I should see the kidney specialist. I think they are waiting to happen something and then they will start the treatment. I feel prevention is better rather than waiting to fail. My own or regular doctor is a general physician. Can you please suggest what should I do? How to find the actual cause of protein in urine? Which test can find it out? I have attached the blood and Urine report here. The reports are as per Danish laboratory standard but it is understandable.

I am unable to accept any records or attached reports. The treatment of low levels of protein in the urine is to control blood pressure and use agents that are either ACE-inhibitors or ARB agents. The Telmisartan that you are … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diet/Nutrition, Hypertension/High Blood Pressure, Kidney Biopsy, Kidney-Related Health Questions, Proteinuria

Doctor, my wife is diagnosed with IgA +3 Disease and advised to take steroids. Her current B/P is 140/90 and proteinuria 4+. Please advise whether steroids are must to take or we can go for alternative medicines?

The use of blood pressure agents such as ACE-inhibitors and ARB agents are most commonly recommeded in patients with Immunoglobuliln A (IgA) nephropathy. Corticosteroids, such as Prednisone or Dexamethasone are also commonly used depending on characteristics found on the kidney … Continue reading

Posted in Ask the Doctor, Hypertension/High Blood Pressure, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions

My 54 year old sister had breast cancer and a double mastectomy 3 years ago. She is also has Type 2 diabetes. On a recent ultrasound, she has a 1.5 cm nodulular mass on her kidney and will be getting a follow up CT scan and blood work. If this is found to be cancer, other than a urologist, what doctors should she see? Nephrologist? Oncologist? Thank you

As a nephrologist, I have no expertise in breast cancer and kidney cancer. I would not be able to offer an opinion about a mass on a kidney. In some cases, an oncologist may be able to offer advice, once … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney Cancer, Kidney-Related Health Questions

My 37 year old cousin has nephrotic syndrome. He has been on medicines since an year. He was improving until last month. However, since last week he is spilling protein again. This is his third relapse in 6 months. He is on predinisolone. The doctor has asked to get a kidney biopsy done. Is there any other way that he can be treated? Also, until when should he be given steroids? I would appreciate your guidance on this.

I would agree that a kidney biopsy is indicated once he has suffered his third relapse. The kidney biopsy will yield a specific diagnosis and this will lead to more specific prognosis and specific treatment. There are many causes of … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrotic Syndrome

Hello. I have had blood in my urine for a couple of years now. They did a culture and all was fine. I then got a kidney ultrasound and it was fine as well. My kidney function continues to decline and now my BUN is elevated and my anion gap is low. I don’t have any swelling, pain etc. Also my folic acid is high. Any ideas? Thank you.

In some cases, when a diagnosis is not evident and kidney function has started to decline, a kidney biopsy may be necessary in order to know what disease you are dealing with and see if any treatment is available.  I … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist

I have a question regarding FSGS. Recently a dear person to me told me that she was diagnosed with MCD when she was 6 years old ( biopsy was taken at that time). Few years later she mentioned that another biopsy was taken which showed FSGS. Ever since she was followed up by nephrologists and was on steroids and in 2010 she was on cellcept until she stopped both steroids and cellcept in 2016. She had testing done and her recent test shows only an elevated ACR of 67 which I’m assuming to be subnephrotic range. All her kidney functions and ultrasounds were normal and so for the past 26 years she has had this condition and kidney function seems fine. My question is what are the chances of her going into ESRD and needing dialysis? I know it is difficult to speculate but given a history of what I’m guessing a stable partial remission FSGS what are the likelyhood of needing dialysis down the road? Do all fsgs patients end up on dialysis? Thank you

Focal and segmental glomerulosclerosis (FSGS) has many different courses and many different presentations. There is not just one clinical course for all patients with FSGS. In fact, minimal change disease (MCD) has often been found to evolve into FSGS when … Continue reading

Posted in Ask the Doctor, FSGS, Kidney Biopsy, Kidney-Related Health Questions, Minimal Change Disease

I have stage 3 kidney disease. I have several tests and still no clue as to why I have at least 2000 mg of protein spewing into my urine. What other reasons are there? I’m 40 and have children. Back in 2016, it was 42, didn’t know and now it is 33. I don’t want to die. I have a biopsy scheduled in a few weeks. No family problems, no high blood pressure or diabetes. Been loosing weight. Drinking lots of water. I am working with specialist but need more answers, Please.

The kidney biopsy should supply the answers you are seeking. There are forms of kidney disease, including glomerulonephritis, that can only be determined with a kidney biopsy. There are no specific blood tests for glomerulonephritis and a biopsy must be … Continue reading

Posted in Ask the Doctor, Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions