Category Archives: Kidney Biopsy

I am male, 30 years old and I have Proteinuria. Doctors suspect some kind of Glomerulonephritis. One doctor thinks is IgA Nephropathy. And I am really confused and worried. I decided to do a biopsy to find out in about a month from now. The laboratory results are confusing me a bit as they use different measurements. All are urine test results here. January 2017: Urinary Micro Albumin: 1132 mg/L Urinary Creatinine: 1.25 gm/L Albumin Creatinine Ratio (ACR) 905.0 mg/gm February 2017: Urinary Micro Albumin: 590 mg/L Urinary Creatinine: 0.60 gm/L Albumin Creatinine Ratio (ACR) 983.0 mg/gm May 2017: Urinary Albumin: 109.2 mg/dL Urinary Creatinine: 0.08 g/dL Albumin Creatinine Ratio (ACR) 1365 mg/g (Different laboratoy than the 2 previous) I will appreciate a lot if you kindly would give me your feedback.

The only result that you quote consistently is the urinary albumin to creatinine ratios.  The other results reflect the concentration of the urine and are not significant.  The urinary albumin to creatinine ratios are between 905 and 1365.  These numbers … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Hydronephrosis and Hydroureter, IgA Nephropathy/IgA Dominant Glomerulonephritis, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist

I am a 51 y.o. caucasian woman with a GFR of 45, Creatinine of 1.27, 4.3 Albumin and BUN of 11. I am overweight, have slightly elevated cholesterol (204) though I exercise religiously 3x a week – 180 minutes total – doing cardio exercise, circuit training, and weight lifting. My BP is pretty average and I am not diabetic. My question is this: Am I at a point that I should pursue treatment with a nephrologist, or is it still relatively early? My GFR has dropped steadily for years and this is the highest creatinine reading I’ve had as well, so I am concerned.

The information that you provide would suggest that you have Stage 3 chronic kidney disease (CKD).  Most primary care physicians (PCP’s) are very capable of managing Stage 3 CKD.  The main treatment for your disease is likely to lose weight, … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Treatments

I had my transplant just under a year and a half ago after being on dialysis for roughly a year. Since transplant my kidney function has been steadily worsening to the point that now I am at 25% function which is where I was when I started dialysis. Two Biopsy have shown no signs of rejection but my most recent creatinine is 2.5 and my proteinuria is 3000. The journey has been very frustrating for me especially since my nephrologist seems to be just “throwing things up against a wall to see what sticks.” The only thing that seemed to improve my situation was being put on prednisone although my DSA showed no reason why that would be the case. Have you heard of any similar cases and what seemed to work for them?

Kidney transplantation is a very inexact science and can be very difficult to anticipate complications and treatments.  In most cases, kidney transplant biopsy should lead to a specific diagnosis of the transplant dysfunction.  In some cases, there can be a … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney Biopsy, Kidney Failure, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Symptoms and Side Effects, Transplantation, Treatments

Respected doctor, I’m from India. My age is 23 years. I’m suffering from nephrotic syndrome. The nephrologist doctor said to me that they have to perform renal/kidney biopsy test before any treatment. So my question is… 1. Is that biopsy test is safe? 2. After biopsy test…will the treatment can cure the kidney disease? 3. Is that any kind of side effects of biopsy? Or after biopsy test treatment?

A kidney biopsy will yield a specific diagnosis which will then result in specific treatment.  It is not possible to predict a cure of the kidney disease, but specific diagnosis will result in more specific treatment options that must be … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrotic Syndrome, Treatments

Dear Doctor, My father (Age 67) is losing lot of protein through urine. He was suspected for Multiple Myeloma but his PET scan and bone marrow biopsy reports were absolutely normal. But the protein loss is still going on and that is causing him lot of weakness. We did his Kidney Functioning Test but that showed nothing serious. He was admitted to ICU because of some urine infection during which lot of water was accumulated in his body. He had swelling on his whole body which now is going away through diuretic medicines prescribed by his cardiologist. Is this related to Kidney or Blood?

Protein in the urine (known as proteinuria) is a finding in kidney disease.  It is first necessary to find out exactly how much protein is spilling into the urine.  If that protein loss is more than 3 grams per day, … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Nephrotic Syndrome, Symptoms and Side Effects, Treatments

Five months ago My daughter (44yrs) was told she has HSP Henoch-Schonlein Purpura. It started with rash on legs that spread throughout. Her kidneys are leaking protein and blood and she is retaining fluid in her legs and painful joints. Her own immune system is destroying her cells and was put on an immunosuppressant drug and mega doses of steroids. Her bowels were bleeding caused by capillary leakage. She had skin biopsy on her rash for Lupus, Lyme and cancer and all negative. Kidney function blood tests are normal. Tomorrow she is scheduled for kidney biopsy to determine a cause for the hematuria and protein that persists in her urine. Have you heard of this virus (in an adult) attacking the kidney and the consequences of this virus ? I would appreciate your views.

Henoch Shoenlein Purpura (HSP) is not caused by any virus that we know of.  The cause of HSP is unknown.  I suggest you wait for the results of the kidney biopsy and then follow the advice of the nephrologist who … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist

As I urinate, I’m losing more proteins than is normal. How can this be treated? I know it has to do with my kidney. Is this serious?

In most cases, the cause of protein loss into the urine (proteinuria) must be evaluated by a nephrologist.  It is often necessary to perform a kidney biopsy to get a specific cause of the proteinuria.  I suggest that you consult … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrologist

Is there a need for long term steroid use in nephrotic syndrome? What causes a flare up? Are there any specialists or recommendations for treatment?

There are many causes of nephrotic syndrome.  In most cases, a kidney biopsy is needed to make a specific diagnosis and this leads to specific treatment of the nephrotic syndrome.  You can read about nephrotic syndrome on our web site … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Nephrologist, Nephrotic Syndrome, Treatments

My kid has Nephrotic Syndrome. Initially he got it at 3 years of age and later on wards every 14 months he relapses. Now his age is 6 running. Is there any other treatment?

There are a number of treatments for nephrotic syndrome, but in cases of recurrent relapse of the disease in children, it is often necessary to perform a kidney biopsy in order to know the exact disease that is being treated, … Continue reading

Posted in Ask the Doctor, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Nephrotic Syndrome, Pediatric Issues, Symptoms and Side Effects

I am a male suffering from nephrotic syndrome since I was 22 . Right now, my age is 28 and when I was 6 years old (in 1996) I got my first attack of severe swelling of body and protein loss. After that the attacks was frequent but not much severe then later it was ok. Again severe attack occurred in 2003 and 2012. I keep on using Prednisone from years and recently in August 2016 doctor suggested to stop using steroid as there no attack from many years, but thing is the relapse occurred after my stoppage of medicine within one month i.e. September 2016. During the attack Prednisone dose usage is 60mg /day and then gradually I will reduce the dose to 5mg/day in alternative days. Now I’m steroid dependent and due to this other complication like high cholesterol and hypertension problems being raised. Recent protein/creatine ratio is 600/177 mg/dl. Please suggest me medications, diet and also estimated cost for the treatment if available. I’m unmarried suggest to me whether I can marry or not, so that the girl whom I marry should not face any problems. Thanking you. Hoping for positive feedback.

The disease that you describe is known as Steroid Dependent Nephrotic Syndrome.  It is a very difficult kidney disease to treat.  In some cases, it is necessary to perform a kidney biopsy in order to know exactly what the kidney … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, FSGS, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Nephrologist, Symptoms and Side Effects, Treatments