Category Archives: Laboratory Testing

Can a creatinine level for 1.7 be reversed for a diabetic patient of 16 years? Feb 2017: Creatinine 1.5 | GFR 54.3, Nov 2017 : Creatinine 1.7 | GFR : 63.2.

The two creatinine determinations that you mention are within typical laboratory error. Laboratory measurement from one day to the next can vary by 0.2 milligrams per deciliter (mg/dl). Hence, these numbers are not clinically different from each other. Future testing … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Laboratory Testing, Serum Creatinine

Dear. Doctor. Good afternoon. Could you kindly explain to me the findings of my brother’s renal ultrasound please? Your feedback will be highly appreciated. Thank you in advance for your time and consideration. Age: 28 Sex: Male Indication: r/o Renal Artery Stenosis RENAL ARTERY DOPPLER/ ABDOMINAL ULTRASOUND REPORT RIGHT LEFT PSV (cm/s) EDV (cm/s) RAR PSV (cm/s) EDV (cm/s) RAR Renal Main Aet @ Ao 105 29 0.67 183 43 1.2 Renal Hilum 70 19 138 38 Interlobular atery 38 12 110 39 Aorta 157 cm/s 157 cm/s RI 0.75 0.78 PI 2.2 1.9 AT 0.130 s 0.150 s The left kidney is normal in size measuring 10.6 x 5.0 cm and contained a 3.7 x 3.0 cm renal cyst within the mid-pole. There was increased echogenicity of the left renal parenchyma and good renal perfusion. Doppler investigations of the left main and intra-renal arteries demonstrate high renal vascular resistance flow showing increased RI vascular resistance (RI=0.78) with decreased diastolic flow. Pulsatility Index (PI) and Acceleration Time (AT) were also increased. These findings strongly suggest medical renal parenchymal disease. The contra-lateral right kidney is small in size measuring approximately 6.1 x 2.3 cm. Color flow doppler and spectral doppler waveforms show abnormally poor or little renal perfusion. Doppler investigation of the right main and interlobular arteries shows increased RI and PI characteristic of parenchymal disease. This small right kidney may be due to congenital hypoplasia or pyelonephritic shrinkage. Both the left and right renal arteries demonstrate normal peak systolic velocities.

The ultrasound with Doppler of both kidneys were done looking for evidence of a blockage in one or both of the kidney arteries. The result suggest that the right kidney is very small. Men should have at least 11 centimeter … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing

I have 1 kidney ( having lost the other to a staghorn calculi, 24 Lithotripsy, Stents and infections -it died off and was removed). My gfr has dropped from 54 in August to 36 on Tuesday. My nephrologist doesn’t seem in the least concerned. His office says he’ll see me in February as planned. Am I wrong to be concerned? I lost my right kidney in 97. Since then I have lived between 50 and 60% function in the left kidney.

Normal estimated glomerular filtration rate (eGFR) for someone with a single kidney is usually within the range of 50 to 60 milliliters per minute per 1.73 meters squared. It is true, that with aging, the eGFR may decline over a … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Nephrectomy / One kidney, Nephrologist

Sir, I am 25 year old man. I have creatinine level of 1.33. It was 1.6 at first checkup. My blood pressure is 140/78 on medicine. The decresing creatinine level indicating my kidneys are reversing from the disease or not? Can you please give your valuable suggestions?

There is some laboratory variability from measurement of serum creatinine from one day to the next, so I am not sure there has been a great deal of change in your kidney function over time. It is difficult to estimate … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Laboratory Testing, Serum Creatinine

My GFR has ranged between 48 to 55 hence stage 3a. In this stage, would a variation of this size be expected with normal lab variation?

Yes, this degree of variation in the estimated glomerular filtration rate (eGFR) would be within the usual expected range of normal laboratory variation. The accuracy with which the laboratory measures the serum creatinine can vary by this degree.

Posted in Ask the Doctor, GFR, Kidney-Related Health Questions, Laboratory Testing, Serum Creatinine

Hi doc. I’m from the Phils. Can you pls explain this further? Right kidney measures 6.4 x 5.7 x 12.9 cm (AP x T x CC). It is displaced anteromedially by a large exophytic fluid attenuating cortical hypodensity at its superior pole measuring 10.9 x 8.1 x 10.8 cm.the mid to lower pole of the right kidney is situated anterior to the aorta and inferior vena cava. The left kidney measures 3.4 x 5.3 x 12.5 cm. Largest on the right is the afformentioned. While on the left measures 8.6 x 7.6 x 7.9 ck. A hyperdense cortical focus is observed in the lower pole of the right kidney measuring 1.0 x0.8 cm possibly a cyst with high protein of hemorrhagic content. A 0.8 x 0.8 m nodule is detected in the genu of the left adrenal gland. Microalbumin Creatinine Assay: MICROALBUMIN 5M1 mg/L CREATININE 82.0 mg/dL A/C Ratio 6.2 mg/g How serious is my condition? What do I need to do? I’m 28 yrs old. Thank you

I cannot make a definitive diagnosis based on the information that you present. It appears that there are several large and small cysts on the kidneys but I cannot tell you why. This will likely require further testing to provide … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Laboratory Testing

Test Report Beta-2 Microglobulin (ß2M) has been identified as the light chain of the HLA-A, -B, and -C major histocompatibility complex antigens, 100 amino acids in length and noncovalently associated with the heavy chain. ß2M occurs on the surface of nucleated cells- abundantly on lymphocytes and monocytes- and on many tumor cell lines. Its function is unknown, but it may control the expression and on the cell surface. Elevated serum concentrations in the presence of a normal glomerular filtration rate suggest increased ß2M production or release. What does this test report of myeloma panel mean? This is the report of patient suffering from chronic kidney disease.

Beta-2-microglobulin can be elevated in patients with chronic kidney disease (CKD) and is often elevated in patients with multiple myeloma. It be elevated in some patients with lymphoma and leukemias. For interpretation, you will have to consult with the physician … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing

Sir, we are going for kidney transplant and want to know what are the test to be done of donor and recipient and how much the results have to be to match? Please send me reply. I shall be very pleased. Thank you.

The testing required for a kidney transplant varies with the transplant center, but in general requires ABO blood type matching, HLA-A, HLA-B and HLA-D testing, as well as cross-matching. In some laboratories, Anti-HLA testing and Panel Reactive Antibody (PRA) testing … Continue reading

Posted in Ask the Doctor, Donation, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Transplantation

Our daughter has kidney stones, and the Dr. says, both kidneys are full of stones. For a period of time she was able to pass the stones, but now she is not passing them. The Dr. is doing another 24 hr urinalysis study, and the same test that any urologist would perform. He is stumped. Would it be to our advantage to seek further treatment from a Doctor that specializes in kidney disease? Her father is a pharmacist, and has suggested for some time our need for someone that can help her. Our fear is that her kidneys will fail and she will go on dialysis. She is 41.

I am not able to make a specific diagnosis based on the information that you present. There are many causes of recurrent and chronic kidney stones. The urologist is the person who is most likely to make a proper diagnosis … Continue reading

Posted in Ask the Doctor, Kidney Stones, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Urological Issues

Recently I got to know that I am having umbilical hernia and pre operative checkup for kidney shows my creatinine level is 1.54 and it is flactuating one day it was 1.54 next day it was 1.23 and day after again it was 1.54. Recently get it checked again it was 1.15 next day 1.2 and again next day it was 1.54 and next day it was 1.2. I don’t have any medical history, I am a vegetarian and don’t eat any kind meat, don’t take any type alcohal or smoke. Don’t have any diabetes, swelling, no high BP, no issue while passing the urine. Blood urea is 21. Can you please suggest why it is happening?

I am unable to make a specific diagnosis of kidney disease based on the information that you present. I suggest that you see your primary care physician for further testing. You should also have a urine test for blood, protein … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Laboratory Testing