Category Archives: Medication and Kidney Disease

I am a 69 y/o white male (retired) who was diagnosed as a CKD Stage 2 patient 3 months ago. A recent lab work showed that my Bicarbonate levels were High, as well as my Glucose and Alkaline Phosphate levels as well. There was an increase in my Bicarbonate, Sodium, Potassium, Chloride, Glucose, Alkaline Phosphate, Bilrubin Total and Total Protein levels from 3 months ago. What do the recent 3 High levels suggest/indicate in regards to my kidneys? Should my nephrologist be concerned with the increase in the 9 areas from 3 months ago? He has added 2 new blood pressure medications in addition to the one I was already taking. My blood pressure reading in his office this afternoon was 154/64. Am I correct in deducting that the blood pressure medications aren’t doing what they are supposed to do? Also, in the time that I have been seeing him, should a biopsy of my kidneys have been taken? What about Xrays or other tests? Should I be seeing another nephrologist who would take a more personal interest in my condition? Are there any advice that you would recommend? Different types of cancer-including kidney and liver- run in my family and I don’t really feel comfortable with the wait-and-see treatment I feel I am getting.

I am unable to accurately interpret laboratory testing without performing a complete history and physical examination. In addition, I would need to know about the laboratory performing the testing to know accuracy and laboratory normals. An elevation in the tests … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diabetes, Hypertension/High Blood Pressure, Kidney Biopsy, Kidney Cancer, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Nephrologist

I have one healthy kidney and one that has shrunk down and non-functioning. My back has gone almost out down toward buttock. Can I take a muscle relaxer in order to get relief? Tylenol is not helping and is the only pain relief drug recommended. Stage 3 and GFR- 48.

I have commonly used muscle relaxers in patients with chronic kidney disease (CKD) and done so safely. You will have to consult with your physician to make sure the dose of the muscle relaxer is adjusted to your level of … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

Is laxative brand Miralax – Polyethylene glycol 3350 safe for the kidneys? Thank you.

Polyethylene Glycol with electrolytes (Brand name Miralax) is safe laxative for patients with chronic kidney disease (CKD).  

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

Does cortisone shots affect kidneys functions?As my husband had acute kidney failure last October and stayed in a hospital for 4 days,the creatinine level was 4.61. And fortunately, his kidneys were regenerated and recovered after 4 days IV and was down to 1.2. Since he was back home, he has blood work every 3 months and back to 1.58. All of a sudden 3 weeks ago, his blood work showed 1.76 that scared us. But he had 3 cortisone shots on his hand 2 weeks before the blood work.Would that cause the number up? Please advise and your prompt attention would be greatly appreciated!

I do not believe cortisone injections should have any effect on the serum creatinine.  Cortisone injections can cause some fluid retention but should not make any changes in the serum creatinine or the estimated glomerular filtration rate (eGFR).  

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Serum Creatinine

I am a psychiatrist and have been using B2 microglobulin for years as a screening tool in my patients taking lithium, in lieu of 24 hr creatinine clearance, for a variety of reasons. Should I be getting serum and urine B2 microglobulin, or is 24 hour creatinine clearance necessary?

Beta 2 microglobulin levels in blood and in some cases urine excretion are commonly elevated in all forms of chronic kidney disease (CKD), but the specificity for CKD is a concern.  Other conditions such as multiple myeloma and myeloproliferative diseases … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Serum Creatinine, Urinary Tract Infection/Pyelonephritis

I am a kidney donor. My Dr wants to give me a cortisone shot in my knee that is buckling due to a fall. Since I only have one kidney are there risks to my single kidney from taking a cortisone shot?

A cortisone shot should not have any significant effect on your remaining kidney function.

Posted in Ask the Doctor, Donation, Kidney-Related Health Questions, Living Donation, Medication and Kidney Disease, Medication and Kidney Function, Nephrectomy / One kidney

What questions should I be asking my nephrologist on my monthly visits?

Common questions are blood pressure control at home, diet instructions, medication side effects and recommendations for follow up.  It is also important to have a general idea as to prognosis for dialysis and transplantation.  I also find many questions about … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, Diet/Nutrition, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function, Nephrologist, Transplantation

I have stage 3 ckd, egfr 50-55, 64 years old male.I also have IBS and occasionally get heartburn, reflux, etc. Is it safe to take meds like Gaviscon or Diovol for symptomatic relief?

Yes. Both Gaviscon and Diovol can be used safely in patients with chronic kidney disease  (CKD). I would suggest that you also review these medications with your physician to make sure they do not interfere with any other medications that … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

In general is it advisable to take a statin drug if one suffers from chronic kidney disease? I have read that some studies have shown that they actually improve gfr slightly.

Statin therapy is indicated for prevention of cardiovascular disease such as congestive heart failure, heart attacks and strokes. While statin therapy may have small effects on kidney function, this is not commonly the reason we use statin therapy. The most … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

I have been on a mix of numerous antidepressants,with some antipsychotic medications, mood stabilizers (no lithium) and antianxiety medications (chiefly BuSpar and Vistaril) for nearly 20 solid years now for severe recurrent depression. My psychiatrist isn’t aware of me being on anything that is known for nephrotoxicity. Could years of continuous multidrug treatment for depression cause some damage to the kidneys?

I am not aware of depression or treatment of depression, outside the use of lithium, to be associated with toxicity to the kidney. Patients with chronic kidney disease are often depressed and require treatment. Patients who are on some of … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function