Category Archives: Medication and Kidney Disease

Just listening to nephrologists podcasts and reading a lot! I have high BP (3 meds) that is not well controlled at all, I’m reading ACE inhibitors are a MUST! I’ve never been prescribed one. My potassium is well within normal limits, I stopped all salt a long time ago, my weight is excellent…my question is why haven’t I been prescribed an ace inhibitor to help control my BP? Also, my PCP refuses to raise or change my diabetes meds! My blood sugar is very high (often 300) I’m on a minimal dosage of Januvia 25 mg once daily. Why? I feel I’m the only one on my Renal team doing anything to slow the progression of my CKD. I’ve been seeing a nephrologist for years…she does nothing more than labs! I’m vegetarian, watch phosphorous, low carbs, no alcohol ever etc. Please advise.

I am not able to answer your questions about your current medical care. I suggest that you review your concerns with your physicians. I find patient advocacy is very helpful in seeking answers to your questions about your current medical … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

SGL2 related sugar, most of time in urine as a permanent thing; can this damage the kidneys in the long run?

I will assume you are asking about Sodium Glucose Cotransport 2 (SGLT2) inhibitors as a treatment for Type 2 diabetes mellitus. These drugs decrease the re-absorption of glucose by the kidney tubules and result in the loss of glucose out … Continue reading

Posted in Ask the Doctor, Diabetes, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

A VA nurse practitioner told me to take 2400 mg of ibuprofen a day for my left elbow pain. I am 70 y/o and have less than one kidney. I told her I was concerned about possible problems but she said it will be fine. Should I be concerned?

I would be concerned about the use of Ibuprofen at a dose of 2400 milligrams daily for any length of time in a patient with chronic kidney disease (CKD). I suggest you have a re-examination.

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease

I have been on Protonix for nine years 40 mg twice a day. I recently saw where PPI’s were identified as potentially causing Kidney disease. My GFR is less than 60 but better than 50. I am considering switching back to Zantac, I would like your opinion on this matter. My doctor says he would rather deal with me taking 80 mg of Protonix every day than the consequences of stopping. I am 70 years old. I would deeply appreciate your opinion on switching to Zantac and/or to continue the Protonix.

I would never overrule you personal physician in giving you an opinion about medical treatment. There are many factors to be considered, including the reason you are taking the Protonix. If you have expressed your concern to your physician, I … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Medication and Kidney Disease

These are my current negative BMP results: CREATININE 1.48 mg/dL; GLUCOSE, RANDOM 207 mg/dL ; BLD UREA NITROGEN 11 mg/dL; GFR NON-AFRICAN AMER 48 mL/min/1.73 m2. What do you think of these? My doc says my kidney filtration remains a bit sluggish so make sure to avoid Advil, Aleve and Ibuprofen type products. You have said, in one of your other answers, that a GFR NON-AFRICAN AMER of 56 mL was early Stage 3 CHRONIC KIDNEY DISEASE (CKD); mine is 48! I am male, 68, 210 lbs, 5’10”. I have had frequent Kidney Stones since I was 30. RXs I take are: Celebrex 200mg twice per day; Viibryd 40mg; Vyvanse 40mg; Lyrica 100mg twice per day; Ambien 10mg at bedtime; Lipitor 40mg; Flomax 0.4mg; Amiloride/HCTZ 2.5-25mg; Lisinopril 20mg; and Tamsulosin 0.4mg. Supplements I take are: Aspirin 81mg; Fish Oil 2,000mg; Vitamin D3 1,500 IU Daily; Vitamin B Complex with C 150mg; Multi Vitamins/Minerals; Magnesium Oxide 400mg; Vitamin E 200IU; and NAC (N-Acetylcysteine) 600mg. Also, my urologist seems unconcerned. But with these numbers “I” am concerned. Thank you.

The estimated glomerular filtration rate (eGFR) between 45 and 59 milliliters per minute per 1.73 meters squared correlates with Stage 3a or early stage chronic kidney disease (CKD) if it has been present for more than three months. I also … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease

On my labs (3 months ago) my GFR NON AFRICAN AMERICAN was 53 ml/min/SA and GFR AFRICAN AMERICAN was 64 ml/min/SA. Is Famotidine 20mg twice a day safe for your kidneys for an extended time? Are there any other H2 Blockers safer than others for an extended period of time? Are medications that decrease stomach acid production not safe at all? Thank you.

The histamine receptor two (H2) blockers are generally thought to be safe for patients with chronic kidney disease (CKD). Famotidine is an example of an H2 blocker. Most H2 blockers are equivalent, except for cimetidine, which can cause an elevation … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Serum Creatinine

I have been on PPI’s for about ten years. I have been on omeprazole for about the last five years. I am a 66 year old white male, with a slightly elevated glucose level (110). I am 5’9″ and weigh 150. I was placed on PPI’s secondary to gastric ulcers and early Barrett’s; I was also diagnosed with polycythemia 8 years ago which is presently controlled with phlebotomies and daily aspirin (another reason PPI’s were suggested). Recently my creatinine has risen to 1.5 and GFR fluctuated between 57 and 44, and I just began seeing a nephrologist. Should I stop taking the PPI?

There is clearly an association between chronic kidney disease (CKD) and the long term use of proton pump inhibitors (PPI’s) such as Omeprazole and others. An association does not necessarily mean a causation, however. I suggest that you review this … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

I suffer from rental tubular acidosis and take high volume of potassium chloride SLOW K & sodium bicarbonate. Both of those, I think, are time release or slow release meds. Well my question is, if I have bariatric surgery specifically RNY BYPASS which creates malabsorption will that affect my intake of potassium and sodium medication??? If so, is there any immediate release medication available??

The sodium bicarbonate is immediate release and the Slow K (potassium chloride) is delayed release. There are forms of potassium, including potassium citrate and potassium bicarbonate that are immediate release. You should discuss this with your physician. Your physician would … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Kidney-Related Health Questions, Medication and Kidney Disease

I am 42 years old. I am diabetic since the age 25. I do regular checks for my kidney test but since 6 months, my protein in kidney goes higher and higher. Recent test shows 1034 protein leakage in kidneys. I am wondering what should I do to stop or lower my kidney leakage for protein? What do you suggest for medicine or diet to fix that problem? How serious is that problem right now? My kidney test is normal as per doctors say but I am very worried about protein in my urine. Doctor advised me to take Lisinopril for 2.5 but now I increased my dose for 10Mg. Any thing else you recommend me to fix this issue? Thanks.

Diabetic kidney disease is present when someone with Type 2 diabetes start spilling excess protein in the urine, when previously they had no protein in the urine. In most cases, this is associated with diabetic eye disease and high blood … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease

I am a healthy, normal weight, non-diabetic, 31 year old Caucasian female. I have had bloodwork done 3 different times over the course of 2 years and my creatinine is consistently over 1.2 mg/dL and my eGFR is consistently under 60 mL/min/1.73m2. I was recently told the reason could be that I am on the oral contraceptive Ocella, which contains the hormone Drospirenone which has antimineralocorticoid activity and can act as a diuretic. However, the person who told me this, is not a physician. Is it possible for consistent abnormal lab work to be caused by Drospirenone or is that unlikely?

I am not aware of any diuretic activity for drospirenone. Drospirenone is a progestin-like compound and can have some anti-mineralocorticoid activity, but this would cause fluid retention and not diuresis. I am not able to provide any other diagnosis based … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function