Category Archives: Medication and Kidney Disease

On my labs (3 months ago) my GFR NON AFRICAN AMERICAN was 53 ml/min/SA and GFR AFRICAN AMERICAN was 64 ml/min/SA. Is Famotidine 20mg twice a day safe for your kidneys for an extended time? Are there any other H2 Blockers safer than others for an extended period of time? Are medications that decrease stomach acid production not safe at all? Thank you.

The histamine receptor two (H2) blockers are generally thought to be safe for patients with chronic kidney disease (CKD). Famotidine is an example of an H2 blocker. Most H2 blockers are equivalent, except for cimetidine, which can cause an elevation … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Serum Creatinine

I have been on PPI’s for about ten years. I have been on omeprazole for about the last five years. I am a 66 year old white male, with a slightly elevated glucose level (110). I am 5’9″ and weigh 150. I was placed on PPI’s secondary to gastric ulcers and early Barrett’s; I was also diagnosed with polycythemia 8 years ago which is presently controlled with phlebotomies and daily aspirin (another reason PPI’s were suggested). Recently my creatinine has risen to 1.5 and GFR fluctuated between 57 and 44, and I just began seeing a nephrologist. Should I stop taking the PPI?

There is clearly an association between chronic kidney disease (CKD) and the long term use of proton pump inhibitors (PPI’s) such as Omeprazole and others. An association does not necessarily mean a causation, however. I suggest that you review this … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

I suffer from rental tubular acidosis and take high volume of potassium chloride SLOW K & sodium bicarbonate. Both of those, I think, are time release or slow release meds. Well my question is, if I have bariatric surgery specifically RNY BYPASS which creates malabsorption will that affect my intake of potassium and sodium medication??? If so, is there any immediate release medication available??

The sodium bicarbonate is immediate release and the Slow K (potassium chloride) is delayed release. There are forms of potassium, including potassium citrate and potassium bicarbonate that are immediate release. You should discuss this with your physician. Your physician would … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Kidney-Related Health Questions, Medication and Kidney Disease

I am 42 years old. I am diabetic since the age 25. I do regular checks for my kidney test but since 6 months, my protein in kidney goes higher and higher. Recent test shows 1034 protein leakage in kidneys. I am wondering what should I do to stop or lower my kidney leakage for protein? What do you suggest for medicine or diet to fix that problem? How serious is that problem right now? My kidney test is normal as per doctors say but I am very worried about protein in my urine. Doctor advised me to take Lisinopril for 2.5 but now I increased my dose for 10Mg. Any thing else you recommend me to fix this issue? Thanks.

Diabetic kidney disease is present when someone with Type 2 diabetes start spilling excess protein in the urine, when previously they had no protein in the urine. In most cases, this is associated with diabetic eye disease and high blood … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease

I am a healthy, normal weight, non-diabetic, 31 year old Caucasian female. I have had bloodwork done 3 different times over the course of 2 years and my creatinine is consistently over 1.2 mg/dL and my eGFR is consistently under 60 mL/min/1.73m2. I was recently told the reason could be that I am on the oral contraceptive Ocella, which contains the hormone Drospirenone which has antimineralocorticoid activity and can act as a diuretic. However, the person who told me this, is not a physician. Is it possible for consistent abnormal lab work to be caused by Drospirenone or is that unlikely?

I am not aware of any diuretic activity for drospirenone. Drospirenone is a progestin-like compound and can have some anti-mineralocorticoid activity, but this would cause fluid retention and not diuresis. I am not able to provide any other diagnosis based … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

Hello, I am 63 years old and have stage 3A CKD where my creatinine fluctuates between 1.4 – 1.6. I have high uric acid (8.6) and every now and then I get some pretty horrific gout attacks. Are any of the medications to lower uric acid safe to take? I currently take 80mg Telmisartan. I understand that Losartan can lower uric acid levels. Does it make sense to switch to Losartan? Thanks.

You are correct that Losartan does have some uric acid lowering properties and may be used in patients with gout and elevated serum uric acid. I suggest that you review this information with your physician and see if Losartan would … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Gout, Kidney-Related Health Questions, Medication and Kidney Disease

I’m 66 years old. My Creatinine op is 1.36. My EST GFR is 52. Protein OP total is 9.2 Is this a concern? What are my next steps to correct this? Thank you.

I am unable to make a specific diagnosis of kidney disease based on the information that you present. There are many causes of chronic kidney disease (CKD). Treatment requires a specific diagnosis and then attempting to delay the progression of … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, dabetes, Diet/Nutrition, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease, Treatments

Hi Dr. I am a 35 year old PD patient. I’ve been doing PD for 3 years and just now caught peritonitis. Heavy dose of Pseudomonas aeruginosa isolated to be exact. I have been given Ciprofloxacin to take orally and after 10 days I am to wash out my bags with Imipenem. It has been 5 days since I was diagnosed and now they are telling me I might have a relapse because they are not being aggressive enough. Is this accurate that you can catch a relapse just like that?

Peritonitis is a very serious infection for a patient on peritoneal dialysis and Pseudomonas infection is a very difficult infection to treat. It is very possible that the Pseudomonas infection is now resistant to the antibiotics and you may suffer … Continue reading

Posted in Ask the Doctor, Dialysis, Kidney-Related Health Questions, Medication and Kidney Disease, Nephrologist

How serious is chronic kidney disease stage 3? What are some symptoms that I may have? I have some swelling and am taking Amiloride 5mg twice a day. Is that OK to take?

Most patients who have Stage 3 chronic kidney disease (CKD) do not have any symptoms at all. That is why the disease is difficult to recognize. Amiloride is a diuretic (water pill) that can cause high blood potassium levels in … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease

PKD has impacted my family for many generations. As time goes on the disease continues to appear in family members but at an older age. Even in the last 100 years family members seem to experience renal failure 20 years later over that span of time (40 versus the current 60). Has a link for this been found by researchers? Thank you.

I am not aware of any consistent data that has looked at this in a long term series of families known to have Polycystic Kidney Disease (PCKD). I would guess that better control of high blood pressure and avoidance of … Continue reading

Posted in Ask the Doctor, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Disease, Polycystic Kidney Disease