Category Archives: Medication and Kidney Disease

Recently diagnosed with CKD stage 3B. Also rheumatoid arthritis diagnosis recently. Is methotrexate safe for me to take?

The dose of Methotrexate must be monitored and sometimes reduced for patients with chronic kidney disease (CKD).  I suggest that you review your concerns with your Rheumatologist and your primary care physician (PCP).  

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Symptoms and Side Effects

My twin sister and I have to to get a MRI or a CT scan to check our aorta every year or two. My sister had a MRI with contrast a year ago and the following day her right leg swelled up and it has continued and is now getting worse around her knee. I had a CT with contrast done a few weeks ago and I had bad pain in my back on the left side. Are we having issues with our kidneys. My sister has gone to emergency room but they don’ t seem to be looking at the kidney. And this all started after the MRI.

I am unable to diagnose any form of kidney disease based on the information that you present.  Magnetic resonance Imaging (MRI) contrast is not known to be toxic to the kidneys, although contrast used for computerized tomography (CT) scanning can … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Symptoms and Side Effects, Treatments

I will be having my first colonoscopy (routine) in a few weeks. I have polycystic kidney disease with no issues at this time. In 2009 I had a cancerous cyst removed near my right kidney and the doctor removed my adrenal gland. The surgery was successful as the cancer was contained in the cyst. I have given the doctor information on my medical history and they recommend my prep be Suprep. My spouse had a colonoscopy a few years ago and he had Prepopik which he said was very tolerable. Unless there is a medical reason I would like to have the prep Prepopik. The lady at the front desk said the doctor would decide what is best for me but I did not like her approach. I have not spoken with a doctor or nurse at this facility. Is there a reason for me not to have the Prepopik. I am thinking of canceling my colonoscopy.

In general, if your estimated glomerular filtration rate (eGFR) is normal, most colonoscopy preparations are safe to take.  Both Prepopik and Suprep contain magnesium, which is not recommended if you have an eGFR of less than 30 milliliters per minute … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Polycystic Kidney Disease, Symptoms and Side Effects, Treatments

Hello sir, Patient’s name is ********. Her Histopathological report: Renal biopsy (5slides for opinion) shows 21 glomeruli, 16 show near global glomerulosclerosis. Remaining shows mild increase in mesangial cellularity, capillary wall thickening with double contouring, endothelial swelling, narrowing and occlusion of capillary lumina(acellular glomeruli). There is segmental fibrin disposition and three fibrocellular crescents are also noted. There is modular tubular atrophy. Histological features favour thrombotic microangiopathy with 70-80% chronicity in all renal compartments. Doctors have suggested Plasma therapy now. The patient had dialysis 5-6 times. Today first session of plasma was administered. It is to be given for 15 days daily to replace the plasma. (Maybe, technically, I am wrong about just the plasma thing) I will be extremely grateful if you could advise the expected course of treatment. I will be online after 23 Hrs. I am from India.

I am unable to make medical recommendations, treatment recommendations or offer a prognosis without performing a complete history and physical examination.  The kidney biopsy suggest that the patient could have Hemolytic Uremic Syndrome (HUS), Thombotic Thrombocytopenic Purpura (TTP), malignant hypertension, … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Symptoms and Side Effects, Treatments

I am 70 and have mccRCC and only about 2/3 of a kidney remaining. My creatinine runs about 2.4 to 2.9 (gfr around 16-19). I also have severe spinal stenosis with leg muscle spasms, particularly at night, causing lack of sleep. I was prescribed tizanidine (2 mg before bed), but on checking online information find that it is cleared through the kidney. Recommended cautions in patients with Chronic Kidney Disease.

I suggest that you consult with your physician and ask if the dosing of the tizanidine is proper for your level of kidney function.  The tizanidine dose may have to be adjusted for you kidney disease.

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function, Treatments

I am male 82 years old. I tested today for 2.0 creatinine. I have been taking for a long period of time 3mg a day of Ativan and 400 mg of Ibuprofen. Could these medicines affect the creatinine level and if so would it raise them that much? About a year ago, it was less than 1.3 and I have only tested again this year to find the high increase.

Ibuprofen can reduce kidney function and should not be taken long term.  I suspect that the abnormalities in your kidney function may be related to the ibuprofen.  I suggest that you stop this medication and then see your primary care … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Symptoms and Side Effects, Treatments

I am at stage 4 kidney disease. My question: If I take a multivitamin, like Centrum Silver, will this hurt my kidneys more?

A multiple vitamin such has Centrum is safe for patients with chronic kidney disease (CKD).

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Treatments

I have a kidney eGFR was 38. Then prescribed Metformin 500 mg 1in morning. Now my eGFR is 27. I think it’s because of metformin? Is it possible?

Metformin is a drug used to treat diabetes and should not be used with an estimated glomerular filtration rate (eGFR) less than 30 milliliters per minute per 1.73 meters squared.  Metformin may cause liver injury with a low eGFR but … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diabetes, GFR, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Symptoms and Side Effects

Hi Doc, I am experiencing the symptoms of kidney disease/failure. I am in a great deal of pain. I need to see someone to address this. I am intolerant to NSAIDS ie Ibuprofen and Naproxen they make me vomit a lot. Any and all ideas on how to get this taken care of would be greatly appreciated.

If you are concerned about kidney disease, you must be examined by your physician and ask to be evaluated. I am unable to make a diagnosis based on the information that you present.  You need to see your physician for … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Treatments

My Husband has CKD stage 4. Last May 2016, he had a UTI and was prescribed trimethoprim. After 4 days he was admitted to hospital with hyperkalemia (6.4) and an acute on chronic kidney injury. He is now on a diet to keep his potassium levels satisfactory. Today his local GP has diagnosed that he has a chest infection and has prescribed amoxicillin 500mg capsules for 7 days. Is this a suitable prescription for a patient with CKD stage 4. Would it be necessary or a worthwhile procedure to have a blood test taken when he has completed the 7-day course to identify if his potassium levels have been affected? What symptoms should one look out for or what tests should be done to check if he is diabetic.

Trimethoprim is known to cause high blood potassium because it interferes with the kidney elimination of potassium.  Penicillins such as amoxicillin do not usually cause potassium problems.  Your husband’s physician should be able to determine if he is a diabetic … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Chronic Kidney Disease, Diabetes, Kidney-Related Health Questions, Laboratory Testing, Medication and Kidney Disease, Medication and Kidney Function, Symptoms and Side Effects, Treatments, Urinary Tract Infection/Pyelonephritis