Category Archives: Medication and Kidney Function

I have had CKD for over 30 years. My GFR is in the mid to high 20’s. I was just diagnosed with Afib. My PCP is recommending warfarin but I read that drugs like Xarelto may be better for kidney patients. Which course of treatment is best for my kidneys?

This is a difficult question to answer. There has only been limited testing of Xarelto (rivaroxaban) and other New Oral Anticoagulants (NOAC’s) in patients with chronic kidney disease (CKD).  There has been much greater experience with the use of Warfarin … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Function

I have GERD, but only feel pain about twice a month. What has worked well for me is to take a TUMS, a Zantac 75mg and drink a can of sparkling water. Always works. I have stage 3 CKD. What should I substitute for the Zantac? What is better, a PPI or H 2 blocker?

Alternatives to Zantac (Ranitidine) that are kidney friendly are Nizatidine (Axid) and Famotidine (Pepcid). I would avoid cimetidine (Tagamet) as it has a side effect of raising the serum creatinine. All of these are Histamine 2 (H2) blockers.

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Function, Serum Creatinine

I have read several articles on the benefits of dapagliflozin (farxiga) not only for diabetic kidney disease but also for other types of kidney diseases. What are your thoughts on this research?

There is considerable evidence that drugs such as Dapagliflozin (Farxiga) and others known as Sodium GLucose co-Transporter 2 (SGLT2) inhibitors improve cardiovascular risk in diabetics and may reduce protein loss in the urine as well as progression of chronic kidney … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

Hello Dr., how are you? My question; is there any alternative medicine against delta cortril for post transplanted patients? Kindly advise.

I am staying safe and at home. I am doing well. Deltacortril is a brand name for Prednisone. Prednisone is the most common drug used for kidney transplantation and it is one of the three used in standard triple therapy … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Medication and Kidney Function, Transplantation

Hi. My Father was treated for Germ Cell Tumor in 2012 but unfortunately chemotherapy badly affected his kidney and my Father was diagnosed with CKD. Today his creatinine is 11.3 mg/dL, eGFR: 4.86 mL/min/1.73m2 and Urea Nitrogen is 132.62 mg/dl. Doctors are recommending Dialysis. But I want sincere advice from you please. We are thinking about getting a kidney transplant as well. What do you think about that? I can share all the reports with you as well. Anxiously waiting for your kind reply.

Your father has very advanced kidney disease. I suggest that you follow the advice of your father’s doctors. The history of the Germ Cell Cancer could complicate consideration of a kidney transplant. I suggest that you continue to consult with … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Function, Transplantation

57 yo male with Polycystic Kidney Disease, BMI 27, non-smoker, Creatine 1.25, eGFR 63. Current Meds: 30mg lisinopril, 12.5mg hydrochlorothiazide daily. Most recent change to Meds: 6 months ago, taking 40 mg lisinopril only, noticed bp increasing so added the HCT. Since starting HCT, hyponatremic at NA = 130. Complaint/Query: Rapid spike in blood pressure over the course of 2-3 days, from well controlled 130/80 to 165/105, which has maintained for the last 7 days and continues. What are possible causes of such a rapid sustained spike? Thank you.

I am unable to make a specific diagnosis without performing a complete history and physical examination. Increasing blood pressure could mean that you need some other blood pressure medication. It could also mean that you are taking in more salt … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Medication and Kidney Function

My mother’s kidneys have been functioning at less than 40% for some years now and a cause still hasn’t been determined even after being in an out of the hospital and regular check ins with a kidney specialist. I have never known her to be in good health in my life; so far she has had periods with depression, headaches, back pain, nausea, vertigo, and now kidney related pain. I’m wondering if hypochondria could actually be causing her kidneys to fail or is it actually possible for kidneys to function as hers are without finding a cause for it? Thanks for your time.

I am not aware of any information that hypochondriasis by itself could cause chronic kidney disease (CKD). From your description, if your mother took large amounts of pain medication including non-steroidal anti-inflammatory drugs (NSAID’s) such as Motrin, Ibuprofen, Aleve, Advil … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Medication and Kidney Disease, Medication and Kidney Function

I have Medullary Sponge Kidney. My urologist says I can take Aleve with a ureter stent. My GP says I shouldn’t take Aleve. What do I do, as the Tylenol does not work for discomfort and the Aleve does? Thanks.

I would tend to side with your Primary Care Physician (PCP) regarding the use of Aleve. The Aleve will decrease your kidney function. Make sure you drink plenty of water to flush the stone fragments out. The pain will likely … Continue reading

Posted in Ask the Doctor, Kidney Stones, Kidney-Related Health Questions, Medication and Kidney Function, Medullary Sponge Kidney

Hi! I have furosemide addiction. How do I stop it? If I stop I get swelling and no urination.

Furosemide is a loop diuretic that removes salt and water from your body. If you use this for a prolonged time when you don’t need to have salt and water removed, your body can retain salt and water when you … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Kidney-Related Health Questions, Medication and Kidney Function

Dear doctor, One and eight months back, I underwent my kidney transplant surgery. For now, I feel well. I just want to know, is it safe to take glutathione supplement as with my condition? Thank you.

The problem is that there have been no studies to evaluate if glutathione will interfere with the drugs that you take to keep your transplant functioning.  I recommend that all of my transplant patients avoid supplements because we do not … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Kidney-Related Health Questions, Medication and Kidney Function, Transplantation