Category Archives: Microalbuminuria

What are your thoughts on using canagliflozin for those with increased albuminuria?

Canagliflozin (Invokana) and Empagliflozin (Jardiance) are Sodium/Glucose cotransporter 2 inhibitors (SGLT2 inhibitors).  They are used to treat Type 2 diabetes and they cause the kidney to eliminate glucose in the urine.  This can lead to weight loss and also can … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, GFR, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Microalbuminuria

I have observed that, total urinary protein, urinary creatinine and urinary microalbumin are commonly measured in laboratory tests for kidney disease patients. It is my understanding that the protein creatinine ratio (P/C) is the ratio of the total urinary protein, which consists of the measurable amount of microalbumin in that test and other proteins, to urinary creatinine. Also calculated in laboratory tests is the urinary microalbumin to urinary creatinine ratio (A/C). I understand that the microalbumin test is more sensitive in order to measure this parameter more accurately but why is it necessary to measure this parameter in the first place and determine the A/C when the P/C also seems to consider the microalbumin? What does the amount of microalbumin in the total protein tell you?

The urinary albumin to creatinine ratio (also commonly called the microalbumin to creatinine ratio) is a much more sensitive test.  The lower limit of detection for the urine albumin to creatinine ratio is commonly in the range of 3-5 micrograms … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Microalbuminuria

I have read in scientific articles that Vitamine B1, B6, and B12 can reverse microalbuminuria in patients. Is this true? Please let me know.

I do not know of any information that B vitamins can have any positive effect on albumin in the urine (microalbuminuria). This is not generally recognized as a treatment for microalbuminuria.

Posted in Ask the Doctor, Kidney-Related Health Questions, Microalbuminuria

I am diabetic and on test on 31.07.18 found my Fasting Glucose (mmol/L) 12.8, Creatinine Serum(umol/L) 90 and Microalbumin(mg/L) 75. Doctor said my earlier tests were shows higher microalbumin but no medications prescribed by other doctors. New doctor said kidney is in trouble on this level. Please advise my status of kidney for any failure or is this able to rectify by medicines. I am vegie, no liquor, smoking or drugs etc. Thanks.

I am not able to interpret the tests that you have quoted. The microalbumin results need to be expressed in terms of milligrams (mg) per gram of creatinine (mg/g) in order for me to interpret the testing. I suggest that … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Microalbuminuria, Nephrologist

Hello Doctor, I am a 54 y/o African American female. I recently had blood work done and my microalbumin was 4.3mg/L. What does that mean? I am a type II diabetic, acid reflux, HP and COPD.

I am unable to interpret the microalbumin result that you present.  The result is a concentration result and only tells me the concentration of albumin in your urine, but this result needs to be divided by the concentration of creatinine … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Microalbuminuria

Dear Doctor, Please see the below recent lab reports for your reference. (Done on 24/06/2017) Urine microalbumin: 983 mg/dl, urine microalbumin/creatine ratio: 1262 mg/dl, Albumin:4.62, creatinine: 1.44, BUN:15.6, Total cholesterol: 275, Uric acid: 8. I have been taking Olmesarten 20 mg for 2 yrs for blood pressure. Then the nephrologist changed this tablet to Lercadip 20 mg, but after taking lercadip, I feel palpitation so again changed to Tab Micardis 40 mg. I have started taking Tab Micardis from last week only. Now the doctor advised me to go for renal biopsy. I am working in Dubai.

I am unable to make a specific diagnosis based on the information that you present.  You have kidney disease based on the increase in urine protein (microalbumin) but I cannot make any other diagnosis.  A kidney biopsy would clearly show … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Kidney Biopsy, Kidney-Related Health Questions, Laboratory Testing, Microalbuminuria, Symptoms and Side Effects, Treatments

Good morning Dr. Spry, I recently reviewed my recent blood work results and after researching that the different tests mean, I’m concerned that I may be showing signs of a kidney issue (note: My grandmother died of Leukemia). My GFR is 60, and my Albumin is 4.9. My ALK Phos is 127, and my Anion Gap is 18. My research indicates that this could mean a possible issue, especially since the GFR has been 60 for my previous 2 blood tests, as well. My ALT is 9, and my CRP is 1.2. My SPEP is 6.6 (noted-“Borderline decreased gamma globulin is seen, no abnormal bands observed”). Thanks very much for your help. If my doctor doesn’t contact me with any concerns, should I bring it to her attention?

I do suggest that you have a urine test for blood, protein and infection.  This may point to some kidney disease.  Otherwise, I am unable to make any diagnosis of kidney disease based on the information that you present.  I … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Microalbuminuria, Symptoms and Side Effects

Years ago, the NKF hosted a screening for kidney disease and I was told my microalbumin was elevated as well as protein. I have regular checkups and my doctor never says anything but labs look good but I see my GFR showing >60. My mom died an ESRD pt. I am 62 and can you recommend where to go for further testing? I do not want kidney failure but I know I have risks.

An estimated glomerular filtration rate (eGFR) greater than 60 milliliters per minute per 1.73 meters squared is a normal eGFR.  If your blood pressure is well controlled and your urine protein is now normal, you may be treated properly.  I suggest that … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Microalbuminuria, Proteinuria, Risk factors

What healthy things can I do to bring my MALB/CRE down to 29?

Lowering the microalbumin to creatinine ratio in the urine is a desirable outcome from any treatment.  The use of ACE-inhibitors and ARB agents have been shown to lower the microalbumin to creatinine ratio in many kidney diseases.  I do not … Continue reading

Posted in Kidney-Related Health Questions, Microalbuminuria, Treatments

I have diagnosed with type 2 diabetes. Last year September my results were HGBA1C 6.2, SUGAR FASTING 103, P/P 170, SERUM CREATININE 8, MICROALBUMIN 300. BP 160/80. After 6 months treatment for BP was Telmisartan 40 daily and Glycomet Sr 500mg 2x daily. I now have a BP of 130/80, fasting sugar is 98, P/P 110 and microalbumin 273. Please advise me on how I can further reduce microalbumin. Am I suffering from CKD? How can I improve kidney function?

In the case of diabetic kidney disease, the goal is to maintain kidney function, once the disease is diagnosed.  If I understand your laboratory values that you have provided, you appear to have chronic kidney disease (CKD) based on an … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Hypertension/High Blood Pressure, Microalbuminuria