Category Archives: Nephrotic Syndrome

My kidney doctor orders lab tests to determine my P/C ratio. My family doctor orders lab tests in order to determine my A/C ratio. From reading some of your previous posts, I understand that the A/C test is more accurate for determining the level of albumin which is a type of protein. What is the purpose of determining these ratios separately; that is, what do these two ratios tell the respective doctors?

The protein to creatinine ratio (P/C ratio) is a measurement of total protein in the urine is often used to measure protein once the excretion rate is more than 200 milligrams per day or a ratio of 200 milligrams per … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Laboratory Testing, Nephrotic Syndrome, Serum Creatinine

I have just posted my question yesterday and you told me that all the sympstoms I stated seems to be not related with CKD as CKD Stage 3 usually doesn’t have any symptoms yet. He has undergone kidney biopsy last December and we are told by the doctors that he has CKD Stage 3 and only 48% of his kidneys is working. As you have said that it may imply other severe kidney diseases, why is it that the biopsy detected that he has CKD? Thank you.

The kidney biopsy is the definitive way to diagnose chronic kidney disease (CKD) and tells you what disease process is causing the kidney damage.  The Stage of CKD is determined by measurement of a glomerular filtration rate (eGFR) and performance … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, GFR, Kidney Biopsy, Kidney-Related Health Questions, Nephrotic Syndrome, Symptoms and Side Effects, Urinary Tract Infection/Pyelonephritis, Urological Issues

My wife, 66 yo, was recently diagnosed with kidney disease early stage kidney failure. Her protein numbers, etal remained somewhat steady for 6 months but on her last two labs they have shot up so the doctor ordered more aggressive treatment which includes prednisone and 2 chemo sessions. She never had a kidney biopsy and cancer has never been diagnosed. In fact by process of elimination the diagnosis is hereditary and high blood pressure. My wife did not ask why chemo if no cancer but I am really upset about it but don’t want to alarm her. Could there be another reason for the chemo? Thank You.

In order for your wife to receive chemotherapy for kidney disease, it is commonly necessary for your wife to sign a permit that she has received informed consent about the use of chemotherapy.  If your wife has not received informed … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney Biopsy, Kidney Cancer, Kidney-Related Health Questions, Lupus, Nephrotic Syndrome

Can gabapetin 300mg taken 3 times a day cause nephotric sydrome and kidney issuses?

I have not seen nephrotic syndrome or kidney issues associated with gabapentin. This would be unusual in my experience.

Posted in Ask the Doctor, Kidney-Related Health Questions, Medication and Kidney Function, Nephrotic Syndrome

Hello, I am concerned that the doctor said my dad needs dialysis because of high creatinine level or something. He asked if stem cell surgery is available in Australia or anywhere in the world? Sorry for my basic and amateur language I am just a young boy concerned for his health. Any answer will be appreciated. Thanks.

There are no stem cell therapies that are currently approved by the Food and Drug Administration (FDA) here in the United States. I am not aware of any stem cell therapy that has been shown to be successful in scientific … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Clinical Trials/Studies, Kidney-Related Health Questions, Nephrotic Syndrome

I’m 18 years old and I have nephrotic syndrome and I also have just one kidney. What future complications can occur?

The nephrotic syndrome is a form of kidney disease that results in loss of excessive protein in the urine and is usually greater than 3.5 grams of protein loss per day. The nephrotic syndrome also results in edema or swelling … Continue reading

Posted in Acute Kidney Injury, Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diet/Nutrition, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Nephrectomy / One kidney, Nephrotic Syndrome

My guy is on dialysis. His spKt/V is .9. I just want to know how low can this number get before he needs to be admitted to the hospital? URR 56, eKt/V .80, stdKt/V 1.71, BFR 422. Rx Duration 3 hours 45 minutes. Please, do not say talk to his DCI clinic. I truly believe he is a test subject to them and his care is not the best. A lot of blood loss from vials and miscalculating the needs so blood leakage there. Been two months of hearing oh they took another vial or oh my needles were leaking etc. Also receiving three MIRCERA in a month 50 mcg. So please give me an answer, when should we get emergency help?

The desirable single pool dialysis clearance (spKt/V) per dialysis session is 1.2 or greater. Hence, his dialysis clearance is inadequate and he either needs more time on dialysis or needs to have his dialysis prescription adjusted. I suggest that you … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Dialysis, Kidney-Related Health Questions, Nephrotic Syndrome

Hello Dr. I am a 59 year old male with a history of kidney stones. I have passed six over the last two decades. I currently have three smaller stones (2mm, 1.6, 2.1) in my right kidney and two stones (2.6 and a whopper at almost 10mm). None of the stones are currently in a position to move into my ureters. My urologist is telling me to have two procedures to remove the stones by going up my penis and blasting them with a laser so they pass. He tells me that as they continue to grow they may affect my kidney function. I’m a retiring military officer and plan to travel extensively starting next year. I surely don’t want to be in some foreign country when one of these stones go south so am inclined to get the procedure. I’m just afraid of damage during the procedure. Should I be worried? Any thoughts appreciated.

I am a nephrologist and do not have surgical expertise. The problem that you describe is a urological problem. A urologist is a surgeon who deals with surgical management of problems related to the urinary tract. I can only suggest … Continue reading

Posted in Ask the Doctor, Kidney Stones, Kidney-Related Health Questions, Nephrotic Syndrome, Urological Issues

Does my CKD Stage III effect the filtration of blood to produce high LDL CHOLESTEROL? I have primary Sjogrens Syndrome, Rheumatoid Arthritis, Fibromyalgia, menopause, Tinnitis, fatty liver, osteoarthritis, TMJ, some sort of neuralgia, neuropathy, hiatal hernia and a slew of delightful ailments that I won’t bore you with. 58 y/o female/ wt: 147/ ht:5′ / active / healthy diet 85% / never smoked / healthy heart. Please advise at your most earliest convenience. I’m anxious to discuss this with you if you have questions or concerns. Respectively Submitted.

Patients who have protein in their urine may produce more bad cholesterol (LDL Cholesterol) as a result of losing important proteins in their urine. This can be known as “nephrotic syndrome” and generally occurs with the amount of protein loss … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Kidney-Related Health Questions, Nephrotic Syndrome

I had NS 3 years old and relapse again at age of 20 years (during the relapse a biopsy was performed and MCD is confirmed). I was treated with prednisolone. Now I am 26 years. In six months 3 relapses continuously occur. l take MMF and Wysolone 10 mg alternate day two week. My urine albumin is faint trace. 1. Is remission is occur? 2. What are the after effects?

The clinical course that you describe is of relapsing nephrotic syndrome (NS). Your biopsy indicates that this is caused by Minimal Change Disease (MCD). If your urine protein (albumin) is undetectable, then it would appear that you are in a … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Minimal Change Disease, Nephrotic Syndrome