Category Archives: Polycystic Kidney Disease

Good evening, sir. My father is suffering from kidney disease. Doctor’s told us this is from genetics. We want to know treatment options, sir?

The treatment of kidney disease is based on a specific diagnosis. There are many forms of genetic kidney disease including polycystic kidney disease, Alport’s Syndrome, FSGS and many others. There are more genetic kidneys diseases being identified each and every … Continue reading

Posted in Alport Syndrome, Ask the Doctor, Chronic Kidney Disease, FSGS, Kidney-Related Health Questions, Polycystic Kidney Disease

Hello Dr. Spry: I am a 79 year old Caucasian male. I have stage 4 Polycystic (PKD1) Kidney disease. I have been monitoring my steady eGFR decline for the past 3 years. In 2/8/17 my Creatinine was 1.83, eGFR 35. As of 9/18/19 my Creatinine was 3.30, eGFR 17. Over that time frame, slightly more than 31 months, my decline was 18. Obviously, quite a substantial loss. For the past 8 months (9/18/19-5/18/20) my eGFR has stabilized at 17, Creatinine 3.23. To me that is good news, no improvement but no deterioration either. Is it possible I could stay at “17” for many months or even several years or am I being just overly optimistic? I take Losartan to control BP, systolic is 126, non smoker, no diabetes, watch my sodium intake (do not own a salt shaker), and exercise regularly. Thank You.

I agree with you that you had a substantial loss of kidney function from 2017 to 2019. That is somewhat atypical for polycystic kidney disease (PCKD). Usually there is a slow steady loss of kidney function in the range of … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, GFR, Kidney-Related Health Questions, Polycystic Kidney Disease

I have polycystic kidney disease and diabetes. I can’t find a medicine for the diabetes that doesn’t cause flank pain and stomach trouble. My doctor doesn’t believe me. I have tried metformin, glipizide and humulin. Can you recommend a med for me?

I am unable to recommend medical therapy without performing a complete history and physical examination. The pain that you get in your flank could be the result of your polycystic kidney disease (PCKD) and not the result of any medication … Continue reading

Posted in Ask the Doctor, Diabetes, Kidney-Related Health Questions, Polycystic Kidney Disease

My 67 year old husband has cyst on both kidneys, the right kidney is totally covered with cysts. His liver also has cyst. What treatment apart from diet change and lots of water would you suggest?

If these are simple cysts, no treatment is required.  However, the number of cysts that you describe could represent the genetic disorder known as autosomal dominant polycystic kidney disease (PCKD).  This diagnosis should be established by your physician or by … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Kidney Cysts, Kidney-Related Health Questions, Nephrologist, Polycystic Kidney Disease

Can kidney cysts cause me to develop polycythemia vera? I also use a CPAP machine because of obstructive apnea. Cpap helps greatly but still making too many red blood cells.

Cystic disease of the kidneys, such as polycystic kidney disease can be associated with polycythemia and increased numbers of red blood cells. Sleep apnea is also associated with polycythemia. If you only have one or two simple cysts, this would … Continue reading

Posted in Ask the Doctor, Kidney Cysts, Kidney-Related Health Questions, Polycystic Kidney Disease

I have PKD in my family (my grandma who passed away, mother who is 56, and other family members) and I am 32 years old. I had my first Ultrasound a few years ago and my latest one last year showed “2 small cysts” and it was also discovered that I only have one kidney. I am seeing a nephrologist in Boca Raton and he has recommended that I get genetic testing done to find out if I have the gene or not since nothing says I have PKD at this point so we want to be sure one way or another. I have reached out to some genetic counseling centers but they are all very busy and I couldn’t get an appointment until June 2020. Is there anything that you can recommend or any specific place I can go for my unique circumstance? Thanks for your help.

Your ultrasound does not achieve criteria for a diagnosis of autosomal dominant polycystic kidney disease (ADPCKD).  The only other criteria that is used is time to see if you develop further cysts that would qualify for a diagnosis of ADPCKD. … Continue reading

Posted in Ask the Doctor, Kidney Cysts, Kidney-Related Health Questions, Nephrologist, Polycystic Kidney Disease

Is the cysts inside the kidneys, can cause kidney failure? In the future, how to take care of this problem and who should I see to follow up? I mean what speciality? Thanks

Cysts on the kidneys may occur as a result of a genetic kidney disease known as autosomal dominant polycystic kidney disease (ADPCKD).  There is also a condition known as acquired cystic disease of the kidney as well as simple cysts … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney Cysts, Kidney-Related Health Questions, Nephrologist, Polycystic Kidney Disease, Urological Issues

BUN 28 mg/dL, Creatinine 1.51 mg/dL, and eGFR (non Afr Am) 51 mL/min/1.73 Should I be concerned? I have ADPKD and am 55 years old.

These findings, if they are repeated and still abnormal, would suggest that you have progressive kidney disease.  You should be followed by your physician and make sure you are on proper treatment for your autosomal dominant polycystic kidney disease (ADPKD). … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, GFR, Kidney-Related Health Questions, Laboratory Testing, Polycystic Kidney Disease, Serum Creatinine

I am contemplating being a kidney donor for my father who has polycystic kidney disease and am trying to find long-term data on health risks for a kidney donor. Most long-term data I have seen to date is very limited in nature and does not cover past 10-12 yrs. Are there any conclusive studies showing anticipated health risks for kidney donors? I am a 48 yr old male, caucasian, 5’9/165 lbs. Thank you for any resources you can point me toward. Regards.

This is difficult to answer for any specific individual. The most comprehensive document that I am aware of is the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors published in … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Donation, Hypertension/High Blood Pressure, Kidney Failure, Kidney-Related Health Questions, Living Donation, Nephrectomy / One kidney, organ donation, Polycystic Kidney Disease

I am a 53 year old woman with polycystic kidney disease. I weigh 115 lbs, my creatinine is 2.0 and my GFR is 28. I’ve had multiple hospitalizations for severe kidney infections and am on preventive antibiotics. Lately I have developed worsening fatigue, nausea, headaches, water retention, kidney pain, mental confusion, joint pain and my recent lab results showed my anion gap is the highest it’s ever been of 25. Is this a sign of metabolic acidosis? I asked my nephrologist if this means I might need dialysis or another form of treatment soon and he seemed like it was nothing, said it’s not time for it yet, my GFR is not low enough yet. How much worse do I need to get before I could benefit from dialysis and get on the transplant list? Is GFR the only indicator with PKD? I am afraid I will be so sick by then that I will not do well. Should I get another opinion. I can no longer work now and I just want to feel better. Thank you for your help.

An anion gap of 25 is a pretty high anion gap and suggests that you may have something other than kidney disease causing your symptoms.  In general, chronic kidney disease (CKD) from polycystic kidney disease (PCKD) causes a non-anion gap … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, GFR, Kidney Cysts, Kidney-Related Health Questions, Nephrologist, Polycystic Kidney Disease, Serum Creatinine