Category Archives: Polycystic Kidney Disease

Dr. I would like to know if Zolpidem and Diazepam could damage even more my kidneys? I have PKD stage 3. Thank you.

Zolpidem is a sleeping medication and Diazepam is a sedative. These medication would be very uncommon as a cause of progressive chronic kidney disease (CKD). Polycystic Kidney Disease (PKD) can certainly show progressive CKD over time. Advertisements

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Polycystic Kidney Disease

I wanted to know about the best treatment option available for Polycyctic kidney disease.How effective is the surgery option? Can a cyst of size exceeding 3.5 cm be operated upon?

Surgery on the cysts of a patient with polycystic kidney disease (PCKD) should rarely be necessary and has generally been abandoned as a treatment for patients with PCKD.  I would recommend that your blood pressure should be very carefully controlled, … Continue reading

Posted in Ask the Doctor, Blood/Urine Testing For Kidney Disease, Hypertension/High Blood Pressure, Kidney-Related Health Questions, Polycystic Kidney Disease, Symptoms and Side Effects, Treatments

My Niece has polycystic kidney disease, as did her Mother (my Half Sister- we had the same Mother different Fathers) and several of her siblings, her GFR is 45. She is 46, her BUN is 30 & creatinine 1.4. Her Mother was diagnosed at age 44 & passed at age 48. Her oldest sister & brother diagnosed at age 44 also. I am curious as to what stage kidney disease she is in and how long she may have before she has to start dialysis. I know only the Good Lord knows some of my questions, but I also know medicine has advanced a lot too. Thank you.

With her estimated glomerular filtration rate (eGFR) being 45 milliliters per minute per 1.73 meters squared, this would be consistent with Stage 3 chronic kidney disease (CKD). Stage 3 CKD is basically an eGFR between 30 and 59 that has … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diet/Nutrition, GFR, Kidney-Related Health Questions, Polycystic Kidney Disease

My Mom has Polycystic Kidney Disease and used to get her cysts drained with a needle. Her Doctor says they dPolycystic Kidney Diseaseo not do that anymore because the risk outweighs the benefits (That the chance of infection is not worth it). She is swollen and in a lot of pain. Does she have any other options for treatment?

It is correct to note that puncture of cysts in patients with Polycystic Kidney Disease (PCKD) is no longer a recommended procedure. It does not appear to be of any benefit and the risks are substantial. I am unable to … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Nephrologist, Polycystic Kidney Disease

I was diagnosed with PKD last year. I am 73 1/2 years old, weigh 185 pounds and am experiencing no symptoms of PKD other than mild skin itching which I control with an over-the-counter allergy medication. My question is: Is there any evidence on whether creatinine tends to increase at a constant rather than an accelerating rate? The following is the recent history of my creatinine levels: April 2015 – 1.32 June 2016 – 1.62 January 2017 – 1.61 August 2017 – 1.7 October 2017 – 1.63 November 2017 – 1.79 If the rate of increase in my creatinine (.47 in 31 months) were constant, it would take 45 years for my creatinine to reach a level of 10. I am following a very strict diet which is very low in sodium, contains very little dairy and no red meat and lots of fruits and vegetables. I am also taking the following supplements to improve my kidney health: astragalus, chitosan, alpha lipoic acid, dandelion root, stinging nettles, sodium bicarbonate and vitamins D3, B12 and B3. And I am taking Lisinopril to keep my blood pressure at approximately 115/65. I take no NSAID’s at all.

Each patient with chronic kidney disease (CKD) and polycystic kidney disease (PKD) is unique and there is no universal truth as to how fast a serum creatinine may change. There is also some variability to the laboratory testing of the … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Kidney-Related Health Questions, Polycystic Kidney Disease, Serum Creatinine

I have a question about deceased donor kidney transplants from 2003. Do they generally last 10-15 years on average or longer? Does one generally die with a functioning transplant? Also, if I have a family history of kidney disease should I be checked again? When I was younger it was said that I did not have it, I assume that’s still the case, but my mom had it, and recently passed away from complications from immune system issues. It’s called PKD.

According to statistics published by the United Network for Organ Sharing (, the expected half life for cadaveric organ transplants in 2003 would have been in the range of 8 to 9 years. This means that on average, one half … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Polycystic Kidney Disease, Transplantation

I have Polycystic CKD with a GFR 42 – 46, BUN 27, Creatnine 1.7. I need to have a cardiac CTA with contrast in preparation for an A-Fib ablation. Could you help me understand the risks of CTA contrast? Thanks very much!

The use of iodinated contrast for computerized tomography (CT) scanning is a risk for patients with underlying chronic kidney disease (CKD). The risk is that patients will suffer acute kidney injury as a result of filtering the contrast through their … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Diet/Nutrition, Kidney-Related Health Questions, Polycystic Kidney Disease

Hello! Would you be able to provide information about some concerns I have for my cousin? She is 54 y.o. and sadly, it appears that her body may have started the end-of-life process. While I don’t know all the exact details, because she has a history of not telling the truth, this is what I know, about 6 yrs ago, she was diagnosed with very advanced of the more serious strain of PKD on both kidneys. Prior to that she went thru 2 open brain surgeries because of aneurysms, which no one said it was linked to PKD. She quickly deteriorated and was put on dialysis. She insisted on Peritoneal because she wanted to do it at home. From the beginning, she didn’t take her illness seriously and continued to eat her regular unhealthy diet, lying to everyone that it didn’t matter. I started to do research about PKD and by asking questions, figured out that it comes from my side of the family. Her mom (72) and her sister (60) both have cysts in their kidneys & liver, but both are in denial, although it has developed as bad as my sister’s. She has 4 adult children and I suggested to them a couple of years ago to get tested, because I read they have a 50/50 of having it. One of her daughters was just diagnosed, the others refuse. I had an ultrasound last year and was negative. My only surviving brother doesn’t want to know. But I digressed sorry. Her kidneys got so large and started getting infected, that she went thru a bilateral nephrectomy to make her feel better. Her doctors told her she had to make changes because she would get more sick, even with PD. She has never been compliant and she was taken off transplant list, which I totally understand because she wouldn’t take care of a new kidney, so doesn’t deserve it. In my opinion she doesn’t want to live any more, but may be afraid of accepting. She has had multiple hospitalizations in the past 24 months, doesn’t eat any more, very frail, no energy, feeling uncomfortable all the time. Last month she went thru parathyroid hyperplasia and thought she wouldn’t make it, but she did. Which brings me to my question, is now too late to even force her to have a transplant so she can live? As I type this, I realize I already know the answer. In your opinion, what can the family do? I’m assuming she doesn’t have much time left. Maybe I just need to mind my own business and let God do his thing! Apologies for my rambling, and thank you for your time.

One of the prime tenets of medical ethics is that a patient is autonomous to make decisions for themselves as long as they are competent. As long as your sister is competent to make decisions, all the decisions that she … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, End of Life Issues, Kidney-Related Health Questions, Polycystic Kidney Disease

I was diagnosed with polycystic kidney disease two years ago. I changed a recommended kidney health diet and light excercise. Lately I have been having pain in my kidneys and adrenal glands along with low energy levels. I have not had a check up since I was diagnosed. What should I do?

Patients with polycystic kidney disease (PCKD) may often experience pain and discomfort from time to time related to cyst growth and cyst hemorrhage. You should avoid wearing tight fitting clothing. You should avoid all forms of caffeine. Light exercise and … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Exercise, Kidney-Related Health Questions, Polycystic Kidney Disease

I was diagnosed with Stage 3 PKD at age 72 with creatinine 1.61 and GFR 42. 14 months later I am at 1.7 and 40. My blood pressure is controlled with 10 mg of lisinopril. My sister was diagnosed with Stage 3 at age 63 and went on dialysis at age 76. Is there any evidence that the disease might follow a similar course in siblings in terms of years to dialysis? Thanks very much for your help.

It is generally thought that Autosomal Dominant Adult Type Polycystic Kidney Disease (PCKD) progresses at about the same rate in any given family.  We recognize two types of PCKD, Type 1 which is younger onset and type 2, which is … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, GFR, Kidney-Related Health Questions, Laboratory Testing, Polycystic Kidney Disease