Category Archives: Transplantation

Hello. I’m 51 yrs old and weigh 73 kg. I had two transplants. 1st in 1994 and 2nd in 2009. Initially, my level after transplant was okay but now my creatine level has started increasing. My latest blood test reports on March 13, 2018 was Creatinine- 1.16 mg/dL BUN/Creat ratio- 18.10 Uric Acid- 9.3 Haemoglobin- 10.8 And this time some of my liver profile parameters are also high. On January 16 2018 was Creatinine- 1.24 Bun/Creat tatio- 10.48 Uric Acid- 6.8 Haemoglobin- 10.7. On August 10 2017 my Tacrolimus- 7.99 Creatinine- 1.08 Uric Acid- 7.8 BUN/Creat ratio- 9.23. Now I’m worried that this is the sudden increase in uric acid because of kidney not functioning properly or maybe because of immunosuppressive drugs or some other reason. And what preventive measures should I take to lower it down. Is this thing reversible? Like can I bring it back to normal level? What are the reasons of such fluctuation in creatinine level?

There is always some variability of the laboratory measurement of the serum creatinine. It is normal laboratory variation for the serum creatinine to change by 0.2 milligrams per deciliter (mg/dl) from day to day. Hence, the variation that you notice … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Serum Creatinine, Transplantation

My 61 year old father was told last week he needs to go on dialysis or get a kidney transplant. I am 41 and in excellent health. However, 4.5 years ago I was diagnosed with Stage 1 invasive breast cancer. It was 6mm. I had a lumpectomy and all of the cancer was removed. It had not spread to my lymph nodes. I also did 6 weeks of radiation. Since then all of my regular breast check ups have been fine. I know there is a lot of testing involved in being a donor, but I would like to know if having had cancer is an automatic disqualifier.

In most situations like this, a transplant center will require that you are cancer free for at least 5 years before allowing you to be a kidney donor. Each transplant center has policies and procedures that are followed in order … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Living Donation, Transplantation

My mother was diagnosed with CKD stage 3B. It is now stage 4. Last test showed her kidneys are only functioning at 23% their normal capacity. I have type O negative blood. If I turn out to be a perfect match, can I donate my kidney anonymously to my mother by contacting her doctor? My sister is power of attorney and claims the doctor said she’s too old to get on a donors list and because her disease is related to high blood pressure, she is automatically disqualified to be on the list. I find this hard to believe. She’s 68 years old. I’ve asked my mum if she’d take one of my kidneys and she says no because I might need it later. If it will save her life, I would do anything. So I’d like to know if a person can anonymously donate a kidney to a family member without the family member having to know where it came from. Thank you. The time before last, her kidney functions where at 28%. Now they’re 23%, so she’s losing them fast and I’d like an answer as soon as possible. Thank you.

I order for you to donate a kidney, your mother must first be evaluated to make sure she is eligible for listing on the transplant list.  In order to be evaluated, her estimated glomerular filtration rate (eGFR) must be less … Continue reading

Posted in Ask the Doctor, Donation, GFR, Kidney-Related Health Questions, Transplantation

When is it decided that dialysis is needed? Stage 4 is the number I was given – what does that mean? Dialysis was said I needed and I chose in the gut. How long can I be on this until a transplant is needed?

The decision to start dialysis is based on a discussion between you and your nephrologist. It is not based on any number or stage. When your symptoms become significant and dialysis is felt to benefit those symptoms, dialysis is often … Continue reading

Posted in Ask the Doctor, Dialysis, GFR, Kidney-Related Health Questions, Nephrologist, Transplantation

Is a magnesium supplement harmful to my 20 year-old transplanted kidney? I take Omeprazole daily which depletes magnesium. I get bad cramps and twitching/burning in my toes and sleep badly.

If your kidney transplant is working normally, a magnesium supplement should not be harmful.  It is true that proton pump inhibitors (PPI’s) such as Omeprazole can result in the kidney wasting magnesium and supplementation may be needed.  I would suggest … Continue reading

Posted in Ask the Doctor, Herbal Supplements in Kidney Disease/Failure, Kidney-Related Health Questions, Transplantation

What’s the possible results for transplant when kidneys are under 45% functioning levels?    

You would not be eligible for listing on the transplant list until your estimated glomerular filtration rate (eGFR) is consistently less than 20 milliliters per minute per 1.73 meters squared.  There is no need to kidney transplantation with an eGFR … Continue reading

Posted in Ask the Doctor, GFR, Kidney-Related Health Questions, Transplantation

My 25 year-old son has ESRD and received a transplanted kidney from my husband 3 years ago. Right now he is married and working long, physically demanding hours, 3-4 days per week, and going to college two days per week. He gets sick (colds, congestion, fatigue) if he has to work more than 3 days per week. His supervisor does not believe him and has “written him up” for missing work when he has been ill. She frequently schedules him for a 4th day of work even though he has repeatedly asked not to be scheduled for more than 3 days/week. I have two questions: Do you have any suggestions for him in this situation? And – Can you advise about whether my son should avoid careers in the medical or construction fields? Those are the two fields that he is considering right now.

The transplant nephrologist who is caring for your son would be the best person to involve in such a decision.  I am not able to give medical advice without performing a complete history and physical examination.  In most cases, a … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Nephrologist, Transplantation

My 69 yr old Mother has recently been diagnosed with a rare kidney disease with no cure. She is starting dialysis soon. She told me only 2 year survival with the dialysis. How is this possible? Can’t a transplant work? I am so uneducated medically. Please explain what you can to me.

I am unable to make a specific diagnosis based on the information that you present.  If your mother has decided to start dialysis therapy, then her kidney function has been determined to be low and her symptoms are such that … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, Kidney-Related Health Questions, Transplantation

I was on Furosemide for a year, but losing weight, proper exercise and diet. I’ve now been off it a year and in good health. My sister may need a kidney in a couple of years (she was just diagnosed with multiple myeloma and receiving chemotherapy for the first 6 weeks, and they hope to broaden it to stem cells transplant). If necessary, I want to make sure I will be able to donate one of mine to her. Is there a preparation I can do to optimize my match to her, and will a doctor be willing to take my kidney if she needs a donor?

There is no specific activity that you could do that would make you a better kidney donor.  Leading a healthy lifestyle, such as not smoking, increasing your extra physical activity by 150 minute per week, eating a healthy diet, and … Continue reading

Posted in Ask the Doctor, Diet/Nutrition, Exercise, Kidney-Related Health Questions, Living Donation, Transplantation

I am 52 yr old female, Caucasian, with Type A blood. My sister is 62 yrs old and is in Stage 4 kidney failure. She is also diabetic. She gets dialysis 3 times per week. I live in CT and she lives in FL. Besides blood type, what do you see as a barrier or barriers from me possibly being able to donate kidney to her? My health history is fairly good with the exception of being diagnosed and treated for Stage 2B HER2+ breast cancer in 2014. I had chemo, surgery and radiation, followed by an additional 6 months of Herceptin to finish my treatment in early 2015. I am considered cancer free. Does that fact exclude me from being a donor? I’m sure there are other factors involved but bases on this information, would I be eligible to help her?

Each transplant center has their own unique criteria for accepting someone as a kidney donor.  There is no universally accepted criteria that is used to accept a potential kidney donor.  Hence, my best advice would be to discuss your situation … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Donation, Kidney-Related Health Questions, Living Donation, Transplantation