Category Archives: Transplantation

Sir, we are going for kidney transplant and want to know what are the test to be done of donor and recipient and how much the results have to be to match? Please send me reply. I shall be very pleased. Thank you.

The testing required for a kidney transplant varies with the transplant center, but in general requires ABO blood type matching, HLA-A, HLA-B and HLA-D testing, as well as cross-matching. In some laboratories, Anti-HLA testing and Panel Reactive Antibody (PRA) testing … Continue reading

Posted in Ask the Doctor, Donation, Kidney-Related Health Questions, Laboratory Testing, Nephrologist, Transplantation

I am 7 & 1/2 years post Kidney Transplant from a live donor. I have had no episodes of rejection and life is good! However, after a regular blood test to checkout the Anibody situation, they have found evidence of a positive antibody being present (layman understanding) My renal bloods are excellent with a Creatinine of 85 (UK). What are my options in managing this situation in terms of now and increase in the possible long term outcome of rejection?

This depends on the type of antibody that has been detected and what the antibody is directed against. There are many different antibodies that can be detected including Anti-HLA antibodies, antibodies against kidney components, viral antibodies, and auto-immune antibodies. I … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Living Donation, Transplantation

Good morning, It is really nice that NKF has this service. My question is about nephropathy. My neprhologist and neurologist simply say that many CKD patients get it. My question is why. There is nothing I have heard that says the kidneys interact directly with the nervous system. Two years ago, I was fine. Hiking, playing basketall and very active for 59. Then I had a little back pain and got some bad medical advice on prescriptions. Caused some brain issues e.g. lesions. I have drop foot and nephropathy but two doctors say these conditions are related to my ESRD. I have been on hemo dialysis for about two years and did PD for a year prior. My guess is that the restrictions on EPO to maintain my hemoglobin below 12 is at least a partial cause. Is this correct? What are the causes based on your knowledge?

From the information that you provide, I will assume you are talking about “neuropathy” and not “nephropathy”. Nephropathy means kidney disease and as you are on dialysis, you obviously have “nephropathy”. Since you mentioned your neurologist, I will assume that … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, Kidney-Related Health Questions, Transplantation

My husband has been on dialysis for over 6 years now and he has had probably 10-12 catheters, 5 FISTULAS and 2 GRAFTS and the HERO GRAFT, and they all have failed. The surgeon said there is nothing else he can do. We are at loss. Does he have any more options? What is the life expectancy of a person just using catheters for dialysis? Any information would be appreciated. Thank you.

The only other options that could be considered are kidney transplantation or peritoneal dialysis. I suggest that you discuss transplantation and peritoneal dialysis with your husband’s nephrologist.

Posted in Ask the Doctor, Dialysis, Kidney-Related Health Questions, Nephrologist, Transplantation

How to decrease creatinine?

There is no medical treatment that will consistently decrease the serum creatinine. Dialysis and transplantation will decrease the serum creatinine, when and if kidney failure occurs. Otherwise the goal of treatment of chronic kidney disease (CKD) is to slow the … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, Kidney-Related Health Questions, Serum Creatinine, Transplantation

I am 70 and have diabetes and kidney disease. I go to VA in Chaleston SC (Wonderful Caring facility). The disease is the result as exposure to agent orange in Vietnam. I am 74 inches tall & 250 lbs. My kidney function is at 21% (has been going down for 6 years) In preparation for a transplant, cardiology found two blockages in my heart that require stents. Problem is that the dye used in heart stents will probably kill my kidneys. I understand that the iodine in the contrast may kill my kidneys. What is the name of the non iodine contrast that maybe less destructive to my kidneys? Any other suggestions you have would be welcome. I am not on dialysis yet. With a three year wait for a transplant killing my kidneys to fix my heart is a tough decision. Thank you.

There are no safe contrast agents that can be used for delivering a heart stent to a coronary artery. The problem that you describe is commonly encountered by patients with advanced chronic kidney disease (CKD).  It is a risk that … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Diabetes, Kidney-Related Health Questions, Nephrologist, Transplantation

I have had a kidney transplant for 39 years. I received it when I was 17 years old. It was a cadaver transplant. I was on Imuran and Prednisone for many years. Last year I was switched to Cell Cept instead of Imuran because of pancreatitis. I now have chronic pancreatitis. I live outside of the US so do not have access to good nephrology care. My question is what can be done about the diarrhea caused by the Cell Cept? I take 500mg twice a day. My creatinine has always been 1.1 or less. I have stomach ulcers, and in one knee, the femur bone has avascular necrosis and I had two strokes in the last three years.

Mycophenolate Mofetil (Cell Cept) is an immunosuppressive drug used to prevent rejection of a kidney transplant and is commonly used when azathioprine (Imuran) cannot be used. It does have significantly different side effects including stomach problems such as nausea, vomiting … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Medication and Kidney Function, Nephrologist, Transplantation

Should higher than normal heart and lung pressures in someone with no kidneys, be removed from transplant list?

The cause of the high heart and lung pressures will have to be determined. If the problem can be treated and corrected, then a kidney transplant might be successful.  In this case, a cardiologist and a pulmonologist (lung specialist) will … Continue reading

Posted in Ask the Doctor, Kidney-Related Health Questions, Transplantation

Hi Dr. I just wanna ask if it is okay to take vitamins that boost immune system like Immunpro if you are a kidney transplant patient?

It is not a good idea to try and boost the immune system if you are taking immune suppressing drugs to keep your kidney transplant functioning. Most of these herbal supplements and vitamin preparations have not been tested with drugs … Continue reading

Posted in Ask the Doctor, Herbal Supplements in Kidney Disease/Failure, Kidney-Related Health Questions, Transplantation

Hello, I have CKD. My right kidney one shut down, when I was in my 20’s. My left kidney one is doing the same thing. My Creatinine is 6.5. I have a donor already to go. All our testing is done but transplant center wants me to do lung rehabilitation. My legs and feet swell up every day. I am so tired every day. You know some people have to wait a long time to get a match. I have one ready. My husband is my donor and they don’t want to do it right now. We were hoping I didn’t have to go on dialysis. We were trying to avoid that. But the transplant center says I may have to go on dialysis right now. Why can’t they do the transplant? No body understands why they won’t just do it. We are good to go. I am getting worse. I can feel it. I don’t want to do anything any more. I’m so tired all the time. Please, I need some body to talk to about this. Thank you!!

I do not know why you are not able to proceed with living donor transplantation.  I can only suggest that you discuss this with your transplant coordinator and your transplant surgeon.  The may be medical issues that must be addressed … Continue reading

Posted in Ask the Doctor, Chronic Kidney Disease, Dialysis, Living Donation, Serum Creatinine, Transplantation