Category Archives: BK virus

My wife had a success cadaver kidney transplant done about 3 years back. However, 6 months ago she was detected with BK virus (Quantitative 150000) and the nephrologist stopped her medicine Mycophenolate Mefotil 500 mg BD. She was given Lefra 20 OD and about a month back the report showed BK virus negative. But suddenly in the last week report, the creatinine has increased from 1.4 to 4.29. The Doctor has biopsy done and the report indicates acute tubulointerstitial nephritis and no rejection. She has been administered Inj.Sumenodrol 500 mg for 3 days and Mycophenolate Mefotil has been restarted. Please advice is the graft kidney safe and medication started by the treating nephrologist in the right direction? Regards.

I am unable to make a specific diagnosis or recommend treatment without performing a complete history and physical examination. The story that you describe is a clinical course I have seen with BK virus reactivation seen in the presence of … Continue reading

Posted in Ask the Doctor, BK virus, Kidney-Related Health Questions, Nephrologist, Transplantation

My brother 54 has undergone kidney transplant surgery in Sep 2017. But he got fever few weeks ago and kidney biopsy shows shows BK viral infection. May I know, is it curable?

BK virus infection of the kidney can cause rejection of the kidney. In most cases, the amount of immune suppression medications must be decreased and carefully monitored in order for the virus to be cleared from the system. Treatment of … Continue reading

Posted in Ask the Doctor, BK virus, Kidney-Related Health Questions, Transplantation

My father had a kidney transplant 2 years ago. He is suffering from urine infection and BKV virus from long time. Yesterday creatinine report was 3.5 and hemoglobin was 6.5. He is also a path of diabetes and BP. Please help what to do? Why creatinine is increasing ?

Patients who suffer from BK virus infection in the urine often develop chronic transplant glomerulopathy and this can lead to transplant failure.  Treating chronic BK virus infection is very difficult. I can only recommend that your father continue to follow … Continue reading

Posted in Ask the Doctor, BK virus, Blood/Urine Testing For Kidney Disease, Chronic Kidney Disease, Diabetes, Kidney Failure, Kidney Stones, Kidney-Related Health Questions, Laboratory Testing, Risk factors, Symptoms and Side Effects, Transplantation, Treatments

I am transplant patient. It has been 6 months since my transplant. Now my serum creatinine had increased to 1.8. The doctor did a biopsy. The biopsy report BK virus positive but blood viral load below 100/ml. Now the doctor suggests to take Leflunomide for two weeks but still the creatinine the same. Please provide me with a consultation.

I am unable to provide medical advice without performing a complete history and physical examination.  I suggest that you continue to consult with your transplant physician.  There are several different ways to evaluate and treat BK virus activation in a … Continue reading

Posted in Ask the Doctor, BK virus, Kidney-Related Health Questions, Transplantation